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M1PPD1

- M1PPD1_HUMAN

UniProt

M1PPD1 - M1PPD1_HUMAN

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Protein
Submitted name:

MHC class I polypeptide-related sequence A

Gene

MICA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation Source: InterPro
  2. immune response Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I polypeptide-related sequence AImported
Gene namesi
Name:MICAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliM1PPD1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

M1PPD1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
PHSLRYNLTV LSWDGSVQSG FLAEVHLDGQ PFLRCDRQKC RAKPQGQWAE
60 70 80 90 100
DVLGNKTWDR ETRDLTGNGK DLRMTLAHIK DQKEGLHSLQ EIRVCEIHED
110 120 130 140 150
NSTRSSQHFY YDGELFLSQN LETEEWTMPQ SSRAQTLAMN VRNFLKEDAM
160 170 180 190 200
KTKTHYHAMH ADCLQELRRY LKSGVVLRRT VPPMVNVTRS EASEGNITVT
210 220 230 240 250
CRASGFYPWN ITLSWRQDGV SLSHDTQQWG DVLPDGNGTY QTWVATRICQ
260 270 280 290 300
GEEQRFTCYM EHSGNHSTHP VPSGKVLVLQ SHWQTFHVSA VAAAAIFVII
310
IFYVRCCKKK TSAAEGP
Length:317
Mass (Da):36,170
Last modified:May 1, 2013 - v1
Checksum:i49B8FE46B0220458
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei317 – 3171Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC171730 Genomic DNA. Translation: AGF90791.1.
UniGeneiHs.130838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC171730 Genomic DNA. Translation: AGF90791.1 .
UniGenei Hs.130838.

3D structure databases

ProteinModelPortali M1PPD1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi MICA. human.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A new variant of MICA*007:01."
    Zollikofer C., Fuerst D., Milnikel I., Richter A.
    Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiM1PPD1_HUMAN
AccessioniPrimary (citable) accession number: M1PPD1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: November 26, 2014
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.