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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cronobacter sakazakii SP291
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei546 – 5461UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:CSSP291_17615Imported
OrganismiCronobacter sakazakii SP291Imported
Taxonomic identifieri956149 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter
ProteomesiUP000011279: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M1JPM3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNEQYSALRS NVSMLGKLLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE
60 70 80 90 100
ADRQALLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPKGEAASN
110 120 130 140 150
PEIIARTLRK LKDQPDINET AIRQAVEALS LELVLTAHPT EITRRTLIHK
160 170 180 190 200
MVEVNNCLKQ LDHKDIADYE RNQIMRRLRQ LIAQSWHTDE IRKNRPSPVD
210 220 230 240 250
EAKWGFAVVE NSLWEGVPNY LRELNEQLEA HLDYKLPVDF VPVRFTSWMG
260 270 280 290 300
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDIQVLISEL SMVECSDALR
310 320 330 340 350
EYVGTEGAQE PYRYLLKGLR AQLLATQAWL EARLKGQKLP KPQGLLTQNE
360 370 380 390 400
QLWEPLYACY ESLVACGLGI IANGELLDTL RRVKAFGVPL VRIDIRQEST
410 420 430 440 450
RHTEALGELT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSDN
460 470 480 490 500
TREVLETCKV IAEAPKGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP
510 520 530 540 550
VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV
560 570 580 590 600
MAASWAQYQA QDALIKTCEK AGIALTLFHG RGGSIGRGGA PAHAALLSQP
610 620 630 640 650
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK
660 670 680 690 700
AAWRHIMDEL SDISCTMYRG YVRENNDFVP YFRSATPEQE LGKLPLGSRP
710 720 730 740 750
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEDGKQDEL
760 770 780 790 800
ETMCRDWPFF STRLGMLEMV FAKADLWLAE YYDQRLVKKE LWPLGRELRQ
810 820 830 840 850
LLEADIKVVL DIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS
860 870 880
RLAEEEGKPA DPCVEQALMV TIAGVAAGMR NTG
Length:883
Mass (Da):98,988
Last modified:May 1, 2013 - v1
Checksum:iA1C99E6D298DCA87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004091 Genomic DNA. Translation: AGE88090.1.
RefSeqiYP_007442379.1. NC_020260.1.

Genome annotation databases

EnsemblBacteriaiAGE88090; AGE88090; CSSP291_17615.
GeneIDi14567933.
KEGGicsz:CSSP291_17615.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004091 Genomic DNA. Translation: AGE88090.1.
RefSeqiYP_007442379.1. NC_020260.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGE88090; AGE88090; CSSP291_17615.
GeneIDi14567933.
KEGGicsz:CSSP291_17615.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Cronobacter sakazakii SP291, a persistent thermotolerant isolate derived from a factory producing powdered infant formula."
    Power K.A., Yan Q., Fox E.M., Cooney S., Fanning S.
    Genome Announc. 1:E0008213-E0008213(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sp291Imported.

Entry informationi

Entry nameiM1JPM3_CROSK
AccessioniPrimary (citable) accession number: M1JPM3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: February 4, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.