ID   M1IUN9_9CREN            Unreviewed;       511 AA.
AC   M1IUN9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_01904};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_01904};
DE            EC=4.1.1.31 {ECO:0000256|HAMAP-Rule:MF_01904};
GN   Name=ppcA {ECO:0000256|HAMAP-Rule:MF_01904};
GN   ORFNames=SacRon12I_00280 {ECO:0000313|EMBL:AGE72312.1};
OS   Sulfolobus acidocaldarius Ron12/I.
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=1028567 {ECO:0000313|Proteomes:UP000011280};
RN   [1] {ECO:0000313|EMBL:AGE72312.1, ECO:0000313|Proteomes:UP000011280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ron12/I {ECO:0000313|EMBL:AGE72312.1,
RC   ECO:0000313|Proteomes:UP000011280};
RX   PubMed=22418622; DOI=10.1038/ismej.2012.20;
RA   Mao D., Grogan D.;
RT   "Genomic evidence of rapid, global-scale gene flow in a Sulfolobus
RT   species.";
RL   ISME J. 6:1613-1616(2012).
CC   -!- FUNCTION: Catalyzes the irreversible beta-carboxylation of
CC       phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon
CC       dicarboxylic acid source for the tricarboxylic acid cycle.
CC       {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01904};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01904};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_01904}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 2 family. {ECO:0000256|HAMAP-
CC       Rule:MF_01904}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP002818; AGE72312.1; -; Genomic_DNA.
DR   RefSeq; WP_015385346.1; NC_020247.1.
DR   AlphaFoldDB; M1IUN9; -.
DR   SMR; M1IUN9; -.
DR   GeneID; 78440414; -.
DR   KEGG; sacr:SacRon12I_00280; -.
DR   PATRIC; fig|1028567.7.peg.55; -.
DR   HOGENOM; CLU_517433_0_0_2; -.
DR   Proteomes; UP000011280; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_01904; PEPcase_type2; 1.
DR   InterPro; IPR007566; PEP_COase_arc-type.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   NCBIfam; TIGR02751; PEPCase_arch; 1.
DR   Pfam; PF14010; PEPcase_2; 1.
DR   PIRSF; PIRSF006677; UCP006677; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_01904, ECO:0000313|EMBL:AGE72312.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01904};
KW   Pyruvate {ECO:0000313|EMBL:AGE72312.1}.
SQ   SEQUENCE   511 AA;  58355 MW;  1337C9AF4012A917 CRC64;
     MRKIPRTMST QHPDNAKVPE WNQGEAISGE NEIIEAYLAF SRYGVEEVMW DAEGKDVDTH
     VVRKLLSQYP EFFRHRILGK DIFLTYRVPN PKIEGAERKV FAETLNTIPI TYDLAEKFYG
     ENPNPPVFEV ILPFTTSYEE LIAVIKFYEK VIVNSDNTKL VDDTYVKDII GETNPKKIEV
     IPLIEDRDSM LRIDTIVGKY IEIERPPYLR VFLARSDPAM NYGLLSAVLS VKYALSRLSK
     MEKIYGVKIF PLLGVGSLPF RGHFSPYNVE NTLNEYRGIY TFTVQSAFKY DYEDDLVISA
     IKKVNGTNVT EKIELSEEDE EIISNVTRKY TQGYQNKIEA LADVINKVAL LLPRRRARKL
     HIGLFGYSRS TGKVTLPRAI SFVGSLYTIG IPPEIIGLSS LSKMTDQELN AIFNNYKYLK
     NDLQFAARFV NFEALQLLKD IWNIDAEVVK AIKEDIDYAE NSLGIRIGES DYMSKKHVLL
     STLALLSIKE GKLDEAKTYI KEMAIVRRAI G
//