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M1IUN9

- M1IUN9_9CREN

UniProt

M1IUN9 - M1IUN9_9CREN

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Sulfolobus acidocaldarius Ron12/I
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Note: Magnesium.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
ORF Names:SacRon12I_00280Imported
OrganismiSulfolobus acidocaldarius Ron12/IImported
Taxonomic identifieri1028567 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000011280: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

M1IUN9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKIPRTMST QHPDNAKVPE WNQGEAISGE NEIIEAYLAF SRYGVEEVMW
60 70 80 90 100
DAEGKDVDTH VVRKLLSQYP EFFRHRILGK DIFLTYRVPN PKIEGAERKV
110 120 130 140 150
FAETLNTIPI TYDLAEKFYG ENPNPPVFEV ILPFTTSYEE LIAVIKFYEK
160 170 180 190 200
VIVNSDNTKL VDDTYVKDII GETNPKKIEV IPLIEDRDSM LRIDTIVGKY
210 220 230 240 250
IEIERPPYLR VFLARSDPAM NYGLLSAVLS VKYALSRLSK MEKIYGVKIF
260 270 280 290 300
PLLGVGSLPF RGHFSPYNVE NTLNEYRGIY TFTVQSAFKY DYEDDLVISA
310 320 330 340 350
IKKVNGTNVT EKIELSEEDE EIISNVTRKY TQGYQNKIEA LADVINKVAL
360 370 380 390 400
LLPRRRARKL HIGLFGYSRS TGKVTLPRAI SFVGSLYTIG IPPEIIGLSS
410 420 430 440 450
LSKMTDQELN AIFNNYKYLK NDLQFAARFV NFEALQLLKD IWNIDAEVVK
460 470 480 490 500
AIKEDIDYAE NSLGIRIGES DYMSKKHVLL STLALLSIKE GKLDEAKTYI
510
KEMAIVRRAI G
Length:511
Mass (Da):58,355
Last modified:May 1, 2013 - v1
Checksum:i1337C9AF4012A917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002818 Genomic DNA. Translation: AGE72312.1.
RefSeqiWP_015385346.1. NC_020247.1.
YP_007435460.1. NC_020247.1.

Genome annotation databases

EnsemblBacteriaiAGE72312; AGE72312; SacRon12I_00280.
GeneIDi14550590.
KEGGisacr:SacRon12I_00280.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002818 Genomic DNA. Translation: AGE72312.1 .
RefSeqi WP_015385346.1. NC_020247.1.
YP_007435460.1. NC_020247.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGE72312 ; AGE72312 ; SacRon12I_00280 .
GeneIDi 14550590.
KEGGi sacr:SacRon12I_00280.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genomic evidence of rapid, global-scale gene flow in a Sulfolobus species."
    Mao D., Grogan D.
    ISME J. 6:1613-1616(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ron12/IImported.

Entry informationi

Entry nameiM1IUN9_9CREN
AccessioniPrimary (citable) accession number: M1IUN9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: November 26, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3