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Protein
Submitted name:

Protein Tnfaip3

Gene

Tnfaip3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-168638. NOD1/2 Signaling Pathway.
R-RNO-5357786. TNFR1-induced proapoptotic signaling.
R-RNO-5357905. Regulation of TNFR1 signaling.
R-RNO-5357956. TNFR1-induced NFkappaB signaling pathway.
R-RNO-936440. Negative regulators of RIG-I/MDA5 signaling.

Protein family/group databases

MEROPSiC64.003.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Tnfaip3Imported
Gene namesi
Name:Tnfaip3Imported
Synonyms:LOC683206Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1589275. Tnfaip3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiM0R7V5.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000065542.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini129 – 300172OTUInterPro annotationAdd
BLAST
Domaini418 – 45336A20-typeInterPro annotationAdd
BLAST
Domaini502 – 53736A20-typeInterPro annotationAdd
BLAST
Domaini539 – 57234A20-typeInterPro annotationAdd
BLAST
Domaini625 – 66036A20-typeInterPro annotationAdd
BLAST
Domaini675 – 71036A20-typeInterPro annotationAdd
BLAST
Domaini734 – 76936A20-typeInterPro annotationAdd
BLAST
Domaini780 – 81435A20-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IQZK. Eukaryota.
ENOG41117NJ. LUCA.
GeneTreeiENSGT00530000062989.
InParanoidiM0R7V5.
KOiK11859.
OMAiETTAMKC.
OrthoDBiEOG7JHM57.

Family and domain databases

InterProiIPR003323. OTU_dom.
IPR002653. Znf_A20.
[Graphical view]
PfamiPF02338. OTU. 1 hit.
PF01754. zf-A20. 4 hits.
[Graphical view]
SMARTiSM00259. ZnF_A20. 7 hits.
[Graphical view]
PROSITEiPS50802. OTU. 1 hit.
PS51036. ZF_A20. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M0R7V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRSNTGVSC RQVYGSSVKG RLTEWAFPLP LQALSRTMAE QLLPQALYLS
60 70 80 90 100
NMRKAVKIRE RTPEDIFKPS NGIIHHFKTM HRYTLEMFRT CQFCPQFREI
110 120 130 140 150
IHKALIDRSV QASLESQKKL NWCREVRKLV ALKTNGDGNC LMHAACQYMW
160 170 180 190 200
GVQDTDLVLR KALCSTLKET DTRNFKFRWQ LESLKSQEFV ETGLCYDTRN
210 220 230 240 250
WNDEWDNLVK MASADTPAAR SGLQYNSLEE IHIFVLSNIL RRPIIVISDK
260 270 280 290 300
MLRSLESGSN FAPLKVGGIY LPLHWPAQEC YRYPIVLGYD SQHFVPLVTL
310 320 330 340 350
KDSGPEIRAV PLVNRERGRF EDLKVHFLTD PEHEMKEKLL KEYLMVLEIP
360 370 380 390 400
VQGWDHGTTH LINAAKLDEA NLPKEINLVD DYFELVQHEY KKWQENGDQG
410 420 430 440 450
RRGAHAQNPL EASTPQLSLM DIKCETPNCP FFMSVNTQPL CHECSERRQK
460 470 480 490 500
NQSKLPKLNS KLGPEGGLPA VGLGSSNWNP EETAGGPHSA PPTAPSLFLF
510 520 530 540 550
SETTAMKCRS PGCPFTLNVQ HNGFCERCHN ARQMSASHTA DPGKCQACLQ
560 570 580 590 600
DVTRTFNGIC STCFKRTTAE PTSSLTSSVP PSCHQRSKSD PSQLIQSLTP
610 620 630 640 650
HSCHRTGNAV PSGYLSQTSR TPADRTGTSK CRKAGCMYFG TPENKGFCTL
660 670 680 690 700
CFIEYRENKQ SVTASGKAAS SAPRFQNNIP CLGRECGTLG STMFEGYCQK
710 720 730 740 750
CFIEAQNQRF HEAKRPEEQL RSSQRREMPR TTQGASRPKC ARASCKNILA
760 770 780 790 800
CRSEELCMEC QHLSQRIASL AHRGEPTPEE PPKQRCRAPA CDHFGNAKCN
810
GYCNECYQFK QMYG
Length:814
Mass (Da):91,942
Last modified:April 3, 2013 - v1
Checksum:i15C9EAD51C60B360
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07000482 Genomic DNA. No translation available.
RefSeqiXP_001060914.4. XM_001060914.5.
XP_003748704.2. XM_003748656.3.

Genome annotation databases

EnsembliENSRNOT00000074583; ENSRNOP00000065542; ENSRNOG00000049517.
GeneIDi683206.
KEGGirno:683206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07000482 Genomic DNA. No translation available.
RefSeqiXP_001060914.4. XM_001060914.5.
XP_003748704.2. XM_003748656.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000065542.

Protein family/group databases

MEROPSiC64.003.

Proteomic databases

PaxDbiM0R7V5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000074583; ENSRNOP00000065542; ENSRNOG00000049517.
GeneIDi683206.
KEGGirno:683206.

Organism-specific databases

CTDi7128.
RGDi1589275. Tnfaip3.

Phylogenomic databases

eggNOGiENOG410IQZK. Eukaryota.
ENOG41117NJ. LUCA.
GeneTreeiENSGT00530000062989.
InParanoidiM0R7V5.
KOiK11859.
OMAiETTAMKC.
OrthoDBiEOG7JHM57.

Enzyme and pathway databases

ReactomeiR-RNO-168638. NOD1/2 Signaling Pathway.
R-RNO-5357786. TNFR1-induced proapoptotic signaling.
R-RNO-5357905. Regulation of TNFR1 signaling.
R-RNO-5357956. TNFR1-induced NFkappaB signaling pathway.
R-RNO-936440. Negative regulators of RIG-I/MDA5 signaling.

Family and domain databases

InterProiIPR003323. OTU_dom.
IPR002653. Znf_A20.
[Graphical view]
PfamiPF02338. OTU. 1 hit.
PF01754. zf-A20. 4 hits.
[Graphical view]
SMARTiSM00259. ZnF_A20. 7 hits.
[Graphical view]
PROSITEiPS50802. OTU. 1 hit.
PS51036. ZF_A20. 7 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (FEB-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiM0R7V5_RAT
AccessioniPrimary (citable) accession number: M0R7V5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: May 11, 2016
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.