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Protein
Submitted name:

Tubulin beta-4A chain

Gene

TUBB4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Tubulin beta-4A chainImported
Gene namesi
Name:TUBB4AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000104833.10.
HGNCiHGNC:20774. TUBB4A.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104833.

PTM / Processingi

Proteomic databases

MaxQBiM0R2D3.
PaxDbiM0R2D3.
PeptideAtlasiM0R2D3.
PRIDEiM0R2D3.

Expressioni

Gene expression databases

BgeeiENSG00000104833.
ExpressionAtlasiM0R2D3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliM0R2D3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 140TubulinInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the tubulin family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1375. Eukaryota.
COG5023. LUCA.
GeneTreeiENSGT00760000119061.

Family and domain databases

Gene3Di3.40.50.1440. 2 hits.
InterProiView protein in InterPro
IPR013838. Beta-tubulin_BS.
IPR002453. Beta_tubulin.
IPR000217. Tubulin.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PANTHERiPTHR11588. PTHR11588. 2 hits.
PfamiView protein in Pfam
PF00091. Tubulin. 1 hit.
PRINTSiPR01163. BETATUBULIN.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
PROSITEiView protein in PROSITE
PS00228. TUBULIN_B_AUTOREG. 1 hit.

Sequencei

Sequence statusi: Fragment.

M0R2D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY
60 70 80 90 100
YNEEFPDRIM NTFSVVPSPK VSDTVVEPYN ATLSVHQLVE NTDETYCIDN
110 120 130 140 150
EALYDICFRT LKLTTPTYGD LNHLVSATMS GVTTCLRFPG QLNADLRKLA

VNMVP
Length:155
Mass (Da):17,400
Last modified:April 3, 2013 - v1
Checksum:i11BD02C106E45BD4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei155Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010503 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000594276; ENSP00000472481; ENSG00000104833.
UCSCiuc060sjn.1. human.

Similar proteinsi

Entry informationi

Entry nameiM0R2D3_HUMAN
AccessioniPrimary (citable) accession number: M0R2D3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: October 25, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported