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Protein
Submitted name:

Tubulin beta-4A chain

Gene

TUBB4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Tubulin beta-4A chainImported
Gene namesi
Name:TUBB4AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000104833.10
HGNCiHGNC:20774 TUBB4A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104833

PTM / Processingi

Proteomic databases

MaxQBiM0R2D3
PeptideAtlasiM0R2D3
PRIDEiM0R2D3

Expressioni

Gene expression databases

BgeeiENSG00000104833
ExpressionAtlasiM0R2D3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0R2D3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 140TubulinInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the tubulin family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1375 Eukaryota
COG5023 LUCA
GeneTreeiENSGT00760000119061

Family and domain databases

Gene3Di3.40.50.1440, 2 hits
InterProiView protein in InterPro
IPR013838 Beta-tubulin_BS
IPR002453 Beta_tubulin
IPR000217 Tubulin
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PANTHERiPTHR11588 PTHR11588, 2 hits
PfamiView protein in Pfam
PF00091 Tubulin, 1 hit
PRINTSiPR01163 BETATUBULIN
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
PROSITEiView protein in PROSITE
PS00228 TUBULIN_B_AUTOREG, 1 hit

Sequencei

Sequence statusi: Fragment.

M0R2D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY
60 70 80 90 100
YNEEFPDRIM NTFSVVPSPK VSDTVVEPYN ATLSVHQLVE NTDETYCIDN
110 120 130 140 150
EALYDICFRT LKLTTPTYGD LNHLVSATMS GVTTCLRFPG QLNADLRKLA

VNMVP
Length:155
Mass (Da):17,400
Last modified:April 3, 2013 - v1
Checksum:i11BD02C106E45BD4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei155Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010503 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000594276; ENSP00000472481; ENSG00000104833
UCSCiuc060sjn.1 human

Similar proteinsi

Entry informationi

Entry nameiM0R2D3_HUMAN
AccessioniPrimary (citable) accession number: M0R2D3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: March 28, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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