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Protein
Submitted name:

Adhesion G protein-coupled receptor E3

Gene

ADGRE3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor E3Imported
Gene namesi
Name:ADGRE3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000131355.14.
HGNCiHGNC:23647. ADGRE3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei143 – 166HelicalSequence analysisAdd BLAST24
Transmembranei178 – 195HelicalSequence analysisAdd BLAST18
Transmembranei207 – 231HelicalSequence analysisAdd BLAST25
Transmembranei251 – 271HelicalSequence analysisAdd BLAST21
Transmembranei291 – 315HelicalSequence analysisAdd BLAST25
Transmembranei335 – 357HelicalSequence analysisAdd BLAST23
Transmembranei363 – 386HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131355.

PTM / Processingi

Proteomic databases

PaxDbiM0R1G2.
PeptideAtlasiM0R1G2.

Expressioni

Gene expression databases

BgeeiENSG00000131355.
ExpressionAtlasiM0R1G2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliM0R1G2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 135GPSInterPro annotationAdd BLAST50
Domaini141 – 387G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST247

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4193. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00900000140800.

Family and domain databases

InterProiView protein in InterPro
IPR017981. GPCR_2-like.
IPR001740. GPCR_2_EMR1-like_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF01825. GPS. 1 hit.
PRINTSiPR01128. EMR1HORMONER.
PR00249. GPCRSECRETIN.
SMARTiView protein in SMART
SM00303. GPS. 1 hit.
PROSITEiView protein in PROSITE
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.

Sequencei

Sequence statusi: Complete.

M0R1G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSMDIRCSD IIQGDTQGPS AIAFISYSSL GNIINATFFE EMDKKDQVYL
60 70 80 90 100
NSQVVSAAIG PKRNVSLSKS VTLTFQHVKM TPSTKKVFCV YWKSTGQGSQ
110 120 130 140 150
WSRDGCFLIH VNKSHTMCNC SHLSSFAVLM ALTSQEEDPV LTVITYVGLS
160 170 180 190 200
VSLLCLLLAA LTFLLCKAIR NTSTSLHLQL SLCLFLAHLL FLVGIDRTEP
210 220 230 240 250
KVLCSIIAGA LHYLYLAAFT WMLLEGVHLF LTARNLTVVN YSSINRLMKW
260 270 280 290 300
IMFPVGYGVP AVTVAISAAS WPHLYGTADR CWLHLDQGFM WSFLGPVCAI
310 320 330 340 350
FSANLVLFIL VFWILKRKLS SLNSEVSTIQ NTRMLAFKAT AQLFILGCTW
360 370 380 390 400
CLGLLQVGPA AQVMAYLFTI INSLQGFFIF LVYCLLSQQV QKQYQKWFRE
410 420 430
IVKSKSESET YTLSSKMGPD SKPSEGDVFP GQVKRKY
Length:437
Mass (Da):48,811
Last modified:April 3, 2013 - v1
Checksum:i88300CB9ABC9946F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022149 Genomic DNA. No translation available.
AC090427 Genomic DNA. No translation available.
AC135052 Genomic DNA. No translation available.
RefSeqiXP_016882872.1. XM_017027383.1.
UniGeneiHs.658712.

Genome annotation databases

EnsembliENST00000599900; ENSP00000471853; ENSG00000131355.
GeneIDi84658.
UCSCiuc060uqh.1. human.

Similar proteinsi

Entry informationi

Entry nameiM0R1G2_HUMAN
AccessioniPrimary (citable) accession number: M0R1G2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: October 25, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported