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Protein
Submitted name:

Interferon regulatory factor 3

Gene

IRF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 3Imported
Gene namesi
Name:IRF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000126456.15
HGNCiHGNC:6118 IRF3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000126456

PTM / Processingi

Proteomic databases

PeptideAtlasiM0R0X9
PRIDEiM0R0X9

Expressioni

Gene expression databases

BgeeiENSG00000126456
ExpressionAtlasiM0R0X9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0R0X9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 102IRF-3InterPro annotationAdd BLAST47

Phylogenomic databases

eggNOGiENOG410IXD8 Eukaryota
ENOG410YA4B LUCA
GeneTreeiENSGT00760000119093

Family and domain databases

Gene3Di2.60.200.10, 1 hit
InterProiView protein in InterPro
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR019471 Interferon_reg_factor-3
IPR017855 SMAD-like_dom_sf
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PfamiView protein in Pfam
PF10401 IRF-3, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit

Sequencei

Sequence statusi: Fragment.

M0R0X9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLAPLPDPG PPSLAVAPEP CPQPLRSPSL DNPTPFPNLG PSENPLKRLL
60 70 80 90 100
VPGEEWEFEV TAFYRGRQVF QQTISCPEGL RLVGSEVGDR TLPGWPVTLP

DPGMS
Length:105
Mass (Da):11,354
Last modified:October 5, 2016 - v8
Checksum:i9BCF740EA7314AE8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei105Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011495 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000593818; ENSP00000471517; ENSG00000126456
UCSCiuc061bgv.1 human

Similar proteinsi

Entry informationi

Entry nameiM0R0X9_HUMAN
AccessioniPrimary (citable) accession number: M0R0X9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 40 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health