ID   M0QZG4_HUMAN            Unreviewed;       122 AA.
AC   M0QZG4;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Zinc finger protein 431 {ECO:0000313|Ensembl:ENSP00000470528.1};
GN   Name=ZNF431 {ECO:0000313|Ensembl:ENSP00000470528.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000470528.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000470528.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000470528.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC010620; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M0QZG4; -.
DR   SMR; M0QZG4; -.
DR   MassIVE; M0QZG4; -.
DR   MaxQB; M0QZG4; -.
DR   PeptideAtlas; M0QZG4; -.
DR   Antibodypedia; 56857; 72 antibodies from 12 providers.
DR   Ensembl; ENST00000599296.5; ENSP00000470528.1; ENSG00000196705.8.
DR   UCSC; uc060wgg.1; human.
DR   HGNC; HGNC:20809; ZNF431.
DR   VEuPathDB; HostDB:ENSG00000196705; -.
DR   GeneTree; ENSGT01100000263507; -.
DR   HOGENOM; CLU_166510_0_0_1; -.
DR   ChiTaRS; ZNF431; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000196705; Expressed in lower esophagus mucosa and 173 other cell types or tissues.
DR   ExpressionAtlas; M0QZG4; baseline and differential.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   Gene3D; 6.10.140.140; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR   PANTHER; PTHR23232:SF112; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:M0QZG4,
KW   ECO:0007829|ProteomicsDB:M0QZG4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          35..106
FT                   /note="KRAB"
FT                   /evidence="ECO:0000259|PROSITE:PS50805"
FT   REGION          96..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   122 AA;  14291 MW;  F25F2C12B2494FD5 CRC64;
     MDDLKYGVYP LKEASGCPGA ERNLLVYSYF EKETLTFRDV AIEFSLEEWE CLNPAQQNLY
     MNVMLENYKN LVFLGVAVSK QDPVTCLEQE KEPWNMKRHE MVDEPPGKTD HDLRLRELEL
     SQ
//