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Protein
Submitted name:

AP-2 complex subunit sigma

Gene

AP2S1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
AP-2 complex subunit sigmaImported
Gene namesi
Name:AP2S1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:565. AP2S1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042753.

PTM / Processingi

Proteomic databases

MaxQBiM0QYZ2.
PaxDbiM0QYZ2.
PeptideAtlasiM0QYZ2.
PRIDEiM0QYZ2.

Expressioni

Gene expression databases

BgeeiENSG00000042753.
ExpressionAtlasiM0QYZ2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263270.

Structurei

3D structure databases

ProteinModelPortaliM0QYZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 157Clat_adaptor_sInterPro annotationAdd BLAST140

Phylogenomic databases

eggNOGiKOG0935. Eukaryota.
COG5030. LUCA.
GeneTreeiENSGT00530000062839.
OMAiSFFDNVC.
OrthoDBiEOG091G0QZV.

Family and domain databases

InterProiIPR016635. AP_complex_ssu.
IPR022775. AP_mu_sigma_su.
IPR000804. Clathrin_sm-chain_CS.
IPR011012. Longin-like_dom.
[Graphical view]
PANTHERiPTHR11753. PTHR11753. 1 hit.
PfamiPF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF015588. AP_complex_sigma. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS00989. CLAT_ADAPTOR_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M0QYZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKGLGKRC KRREDLEIRF ILIQNRAGKT RLAKWYMQFD DDEKQKLIEE
60 70 80 90 100
VHAVVTVRDA KHTNFVEFRN FKIIYRRYAG LYFCICVDVN DNNLAYLEAI
110 120 130 140 150
HNFVEVLNEY FHNVCELDLV FNFYKVYTVV DEMFLAGEIR ETSQTKVLKQ

LLMLQSLE
Length:158
Mass (Da):18,929
Last modified:April 3, 2013 - v1
Checksum:i685BDAF358F5893D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008622 Genomic DNA. No translation available.
AC098794 Genomic DNA. No translation available.
RefSeqiNP_001288005.1. NM_001301076.1.
UniGeneiHs.119591.

Genome annotation databases

EnsembliENST00000601498; ENSP00000470176; ENSG00000042753.
GeneIDi1175.
UCSCiuc061ajp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008622 Genomic DNA. No translation available.
AC098794 Genomic DNA. No translation available.
RefSeqiNP_001288005.1. NM_001301076.1.
UniGeneiHs.119591.

3D structure databases

ProteinModelPortaliM0QYZ2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263270.

Proteomic databases

MaxQBiM0QYZ2.
PaxDbiM0QYZ2.
PeptideAtlasiM0QYZ2.
PRIDEiM0QYZ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000601498; ENSP00000470176; ENSG00000042753.
GeneIDi1175.
UCSCiuc061ajp.1. human.

Organism-specific databases

CTDi1175.
HGNCiHGNC:565. AP2S1.
OpenTargetsiENSG00000042753.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0935. Eukaryota.
COG5030. LUCA.
GeneTreeiENSGT00530000062839.
OMAiSFFDNVC.
OrthoDBiEOG091G0QZV.

Miscellaneous databases

ChiTaRSiAP2S1. human.
GenomeRNAii1175.

Gene expression databases

BgeeiENSG00000042753.
ExpressionAtlasiM0QYZ2. baseline and differential.

Family and domain databases

InterProiIPR016635. AP_complex_ssu.
IPR022775. AP_mu_sigma_su.
IPR000804. Clathrin_sm-chain_CS.
IPR011012. Longin-like_dom.
[Graphical view]
PANTHERiPTHR11753. PTHR11753. 1 hit.
PfamiPF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF015588. AP_complex_sigma. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS00989. CLAT_ADAPTOR_S. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiM0QYZ2_HUMAN
AccessioniPrimary (citable) accession number: M0QYZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 2, 2016
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.