Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

AP complex subunit sigma

Gene

AP2S1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
AP complex subunit sigmaUniRule annotation
Gene namesi
Name:AP2S1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000042753.11.
HGNCiHGNC:565. AP2S1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042753.

PTM / Processingi

Proteomic databases

MaxQBiM0QYZ2.
PaxDbiM0QYZ2.
PeptideAtlasiM0QYZ2.
PRIDEiM0QYZ2.

Expressioni

Gene expression databases

BgeeiENSG00000042753.
ExpressionAtlasiM0QYZ2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliM0QYZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 157Clat_adaptor_sInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the adaptor complexes small subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0935. Eukaryota.
COG5030. LUCA.
GeneTreeiENSGT00900000141140.
OMAiSFFDNVC.
OrthoDBiEOG091G0QZV.

Family and domain databases

InterProiView protein in InterPro
IPR016635. AP_complex_ssu.
IPR022775. AP_mu_sigma_su.
IPR027156. APS2.
IPR000804. Clathrin_sm-chain_CS.
IPR011012. Longin-like_dom_sf.
PANTHERiPTHR11753. PTHR11753. 1 hit.
PTHR11753:SF6. PTHR11753:SF6. 1 hit.
PfamiView protein in Pfam
PF01217. Clat_adaptor_s. 1 hit.
PIRSFiPIRSF015588. AP_complex_sigma. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS00989. CLAT_ADAPTOR_S. 1 hit.

Sequencei

Sequence statusi: Complete.

M0QYZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLKGLGKRC KRREDLEIRF ILIQNRAGKT RLAKWYMQFD DDEKQKLIEE
60 70 80 90 100
VHAVVTVRDA KHTNFVEFRN FKIIYRRYAG LYFCICVDVN DNNLAYLEAI
110 120 130 140 150
HNFVEVLNEY FHNVCELDLV FNFYKVYTVV DEMFLAGEIR ETSQTKVLKQ

LLMLQSLE
Length:158
Mass (Da):18,929
Last modified:April 3, 2013 - v1
Checksum:i685BDAF358F5893D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008622 Genomic DNA. No translation available.
AC098794 Genomic DNA. No translation available.
RefSeqiNP_001288005.1. NM_001301076.1.
UniGeneiHs.119591.

Genome annotation databases

EnsembliENST00000601498; ENSP00000470176; ENSG00000042753.
GeneIDi1175.
UCSCiuc061ajp.1. human.

Similar proteinsi

Entry informationi

Entry nameiM0QYZ2_HUMAN
AccessioniPrimary (citable) accession number: M0QYZ2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 22, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported