Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interferon regulatory factor 3

Gene

IRF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 3Imported
Gene namesi
Name:IRF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000126456.15
HGNCiHGNC:6118 IRF3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000126456

PTM / Processingi

Proteomic databases

MaxQBiM0QYT9
PeptideAtlasiM0QYT9

Expressioni

Gene expression databases

BgeeiENSG00000126456

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 234IRF-3InterPro annotationAdd BLAST180

Phylogenomic databases

eggNOGiENOG410IXD8 Eukaryota
ENOG410YA4B LUCA
GeneTreeiENSGT00760000119093

Family and domain databases

Gene3Di2.60.200.101 hit
InterProiView protein in InterPro
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR019471 Interferon_reg_factor-3
IPR017855 SMAD-like_dom_sf
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PfamiView protein in Pfam
PF10401 IRF-3, 1 hit
SMARTiView protein in SMART
SM01243 IRF-3, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit

Sequencei

Sequence statusi: Complete.

M0QYT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLAPLPDPG PPSLAVAPEP CPQPLRSPSL DNPTPFPNLG PSENPLKRLL
60 70 80 90 100
VPGEEWEFEV TAFYRGRQVF QQTISCPEGL RLVGSEVGDR TLPGWPVTLP
110 120 130 140 150
DPGMSLTDRG VMSYVRHVLS CLGGGLALWR AGQWLWAQRL GHCHTYWAVS
160 170 180 190 200
EELLPNSGHG PDGEVPKDKE GGVFDLGPFI VDLITFTEGS GRSPRYALWF
210 220 230 240 250
CVGESWPQDQ PWTKRLVMVK VVPTCLRALV EMARVGGASS LENTVDLHIS
260 270 280
NSHPLSLTSD QYKAYLQDLV EGMDFQGPGE S
Length:281
Mass (Da):30,779
Last modified:April 3, 2013 - v1
Checksum:iBD1CD8A841ACF200
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011495 Genomic DNA No translation available.
RefSeqiNP_001184054.1, NM_001197125.1
NP_001184055.1, NM_001197126.1
UniGeneiHs.289052
Hs.731922
Hs.75254

Genome annotation databases

EnsembliENST00000377135; ENSP00000366339; ENSG00000126456
ENST00000593922; ENSP00000472601; ENSG00000126456
ENST00000598808; ENSP00000472582; ENSG00000126456
ENST00000599144; ENSP00000470069; ENSG00000126456
GeneIDi3661
UCSCiuc021uxp.2 human

Similar proteinsi

Entry informationi

Entry nameiM0QYT9_HUMAN
AccessioniPrimary (citable) accession number: M0QYT9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: April 25, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported