ID   M0QXZ2_HUMAN            Unreviewed;       106 AA.
AC   M0QXZ2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Zinc finger protein 528 {ECO:0000313|Ensembl:ENSP00000469481.1};
GN   Name=ZNF528 {ECO:0000313|Ensembl:ENSP00000469481.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000469481.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000469481.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000469481.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC010332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M0QXZ2; -.
DR   SMR; M0QXZ2; -.
DR   MassIVE; M0QXZ2; -.
DR   PeptideAtlas; M0QXZ2; -.
DR   Antibodypedia; 32595; 24 antibodies from 9 providers.
DR   Ensembl; ENST00000594530.1; ENSP00000469481.1; ENSG00000167555.14.
DR   UCSC; uc061cdr.1; human.
DR   HGNC; HGNC:29384; ZNF528.
DR   VEuPathDB; HostDB:ENSG00000167555; -.
DR   GeneTree; ENSGT00940000163013; -.
DR   ChiTaRS; ZNF528; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000167555; Expressed in buccal mucosa cell and 120 other cell types or tissues.
DR   ExpressionAtlas; M0QXZ2; baseline and differential.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   Gene3D; 6.10.140.140; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR   PANTHER; PTHR23232:SF147; KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:M0QXZ2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          8..79
FT                   /note="KRAB"
FT                   /evidence="ECO:0000259|PROSITE:PS50805"
FT   REGION          80..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  11855 MW;  11862C664208A8D2 CRC64;
     MALTQGPLKF MDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLGIC LPDLSVTSML
     EQKRDPWTLQ SEEKIANDPD GRECIKGVNT GESSGGQSGG PIIFVF
//