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L8IUK1

- L8IUK1_9CETA

UniProt

L8IUK1 - L8IUK1_9CETA

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Protein
Submitted name:

Coagulation factor XIII A chain

Gene

M91_12590

Organism
Bos mutus
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei315 – 3151UniRule annotation
Active sitei374 – 3741UniRule annotation
Active sitei397 – 3971UniRule annotation
Metal bindingi437 – 4371CalciumUniRule annotation
Metal bindingi439 – 4391CalciumUniRule annotation
Metal bindingi486 – 4861CalciumUniRule annotation
Metal bindingi491 – 4911CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Gene namesi
ORF Names:M91_12590Imported
OrganismiBos mutusImported
Taxonomic identifieri72004 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Family & Domainsi

Phylogenomic databases

KOiK03917.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L8IUK1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSESSGTAFG GRRAIPPNTS NAAENDPPTV ELQGLVPRGF NPQDYLNVTN
60 70 80 90 100
VHLFKERWDS NKVDHHTDKY SNDKLIVRRG QSFYIQIDFN RPYDPRRDLF
110 120 130 140 150
RVEYVIGLYP QENKGTYIPV PLVSELQSGK WGAKVVMRED RSVRLSVQSS
160 170 180 190 200
ADCIVGKFRM YVAVWTPYGV IRTSRNPETD TYILFNPWCE EDAVYLENEK
210 220 230 240 250
EREECVLNDI GVIFYGDFND IKSRSWSYGQ FEDSILDACL FVMDKANMDL
260 270 280 290 300
SGRGNPIKVS RVGSAMINAK DDEGVIAGSW DNVYAYGVPP SAWTGSVDIL
310 320 330 340 350
LEYKSSQKPV RYGQCWVFAG VFNTFLRCLG IPARVVTNYF SAHDNDANLQ
360 370 380 390 400
LDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQVVDSTP
410 420 430 440 450
QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL VYVTAKKDGT
460 470 480 490 500
HVVEALDTTH IGKLIVTKEI GGDGMKDITD TYKFQEGQEE ERLALETAMM
510 520 530 540 550
YGAKKALNTE GVLKSKSDVR MNFEVENAVL GRDLKVIITF RNNGSARYTV
560 570 580 590 600
TAYLSGNISF YTGVSKAEFK NETFEVTLEP LSFKREEVLI GAGEYMGQLL
610 620 630 640 650
EQAFLHFFVT ARVNETRDVL AKQKSIALTV PKVVIKVRGA QVVGSDMVVT
660 670 680 690 700
VEFTNPLKET LRNVWIRLDG PGVTKPLRKM FREIRPNSTV QWEELCRPWV
710 720 730
SGPRKLIASL TSDSLRHVYG ELDLQIQRRP SM
Length:732
Mass (Da):82,731
Last modified:April 3, 2013 - v1
Checksum:iC6BBE8B7D374D697
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JH880690 Genomic DNA. Translation: ELR59683.1.
RefSeqiXP_005891215.1. XM_005891153.1.

Genome annotation databases

GeneIDi102282528.
KEGGibom:102282528.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JH880690 Genomic DNA. Translation: ELR59683.1 .
RefSeqi XP_005891215.1. XM_005891153.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 102282528.
KEGGi bom:102282528.

Organism-specific databases

CTDi 2162.

Phylogenomic databases

KOi K03917.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: YakQH1Imported.

Entry informationi

Entry nameiL8IUK1_9CETA
AccessioniPrimary (citable) accession number: L8IUK1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: October 1, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)