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L8IUK1

- L8IUK1_9CETA

UniProt

L8IUK1 - L8IUK1_9CETA

Protein
Submitted name:

Coagulation factor XIII A chain

Gene

M91_12590

Organism
Bos mutus
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei315 – 3151UniRule annotation
    Active sitei374 – 3741UniRule annotation
    Active sitei397 – 3971UniRule annotation
    Metal bindingi437 – 4371CalciumUniRule annotation
    Metal bindingi439 – 4391CalciumUniRule annotation
    Metal bindingi486 – 4861CalciumUniRule annotation
    Metal bindingi491 – 4911CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Coagulation factor XIII A chainImported
    Gene namesi
    ORF Names:M91_12590Imported
    OrganismiBos mutusImported
    Taxonomic identifieri72004 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

    Family & Domainsi

    Phylogenomic databases

    KOiK03917.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    L8IUK1-1 [UniParc]FASTAAdd to Basket

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    MSESSGTAFG GRRAIPPNTS NAAENDPPTV ELQGLVPRGF NPQDYLNVTN    50
    VHLFKERWDS NKVDHHTDKY SNDKLIVRRG QSFYIQIDFN RPYDPRRDLF 100
    RVEYVIGLYP QENKGTYIPV PLVSELQSGK WGAKVVMRED RSVRLSVQSS 150
    ADCIVGKFRM YVAVWTPYGV IRTSRNPETD TYILFNPWCE EDAVYLENEK 200
    EREECVLNDI GVIFYGDFND IKSRSWSYGQ FEDSILDACL FVMDKANMDL 250
    SGRGNPIKVS RVGSAMINAK DDEGVIAGSW DNVYAYGVPP SAWTGSVDIL 300
    LEYKSSQKPV RYGQCWVFAG VFNTFLRCLG IPARVVTNYF SAHDNDANLQ 350
    LDIFLEEDGN VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQVVDSTP 400
    QENSDGMYRC GPASVQAIKH GHVCFQFDAP FVFAEVNSDL VYVTAKKDGT 450
    HVVEALDTTH IGKLIVTKEI GGDGMKDITD TYKFQEGQEE ERLALETAMM 500
    YGAKKALNTE GVLKSKSDVR MNFEVENAVL GRDLKVIITF RNNGSARYTV 550
    TAYLSGNISF YTGVSKAEFK NETFEVTLEP LSFKREEVLI GAGEYMGQLL 600
    EQAFLHFFVT ARVNETRDVL AKQKSIALTV PKVVIKVRGA QVVGSDMVVT 650
    VEFTNPLKET LRNVWIRLDG PGVTKPLRKM FREIRPNSTV QWEELCRPWV 700
    SGPRKLIASL TSDSLRHVYG ELDLQIQRRP SM 732
    Length:732
    Mass (Da):82,731
    Last modified:April 3, 2013 - v1
    Checksum:iC6BBE8B7D374D697
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JH880690 Genomic DNA. Translation: ELR59683.1.
    RefSeqiXP_005891215.1. XM_005891153.1.

    Genome annotation databases

    GeneIDi102282528.
    KEGGibom:102282528.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JH880690 Genomic DNA. Translation: ELR59683.1 .
    RefSeqi XP_005891215.1. XM_005891153.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 102282528.
    KEGGi bom:102282528.

    Organism-specific databases

    CTDi 2162.

    Phylogenomic databases

    KOi K03917.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: YakQH1Imported.

    Entry informationi

    Entry nameiL8IUK1_9CETA
    AccessioniPrimary (citable) accession number: L8IUK1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2013
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)