ATL1-alpha

Functionⁱ

GO - Molecular functionⁱ

RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Source: Ensembl

Complete GO annotation...

GO - Biological processⁱ

alpha-beta T cell differentiation Source: Ensembl
commitment of neuronal cell to specific neuron type in forebrain Source: Ensembl
epithelial cell morphogenesis Source: Ensembl
keratinocyte development Source: Ensembl
negative regulation of apoptotic process Source: Ensembl
negative regulation of cell proliferation Source: Ensembl
odontogenesis of dentin-containing tooth Source: Ensembl
olfactory bulb axon guidance Source: Ensembl
positive T cell selection Source: Ensembl
post-embryonic camera-type eye development Source: Ensembl
regulation of keratinocyte proliferation Source: Ensembl
regulation of lipid metabolic process Source: Ensembl
regulation of neuron differentiation Source: Ensembl
striatal medium spiny neuron differentiation Source: Ensembl
T cell differentiation in thymus Source: Ensembl
T cell receptor V(D)J recombination Source: Ensembl
thymus development Source: Ensembl

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ATL1-alpha zinc finger proteinImported Submitted name: B-cell CLL/lymphoma 11B (Zinc finger protein), isoform CRA_bImported
Gene namesⁱ	Name:ATL1-alphaImported Synonyms:BCL11BImported ORF Names:hCG_1657560Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

GO - Cellular componentⁱ

neuron projection Source: Ensembl
nucleus Source: Ensembl

Complete GO annotation...

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000127152.
ExpressionAtlasⁱ	L8B7P7. baseline and differential.

Structureⁱ

3D structure databases

SMRⁱ	L8B7P7.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	221 – 244	C2H2-typeInterPro annotationAdd BLAST	24
Domainⁱ	427 – 454	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	455 – 482	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	796 – 823	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	824 – 846	C2H2-typeInterPro annotationAdd BLAST	23
Domainⁱ	854 – 877	C2H2-typeInterPro annotationAdd BLAST	24

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
OMAⁱ	DDAGGCG.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G160N.

Family and domain databases

InterProⁱ	View protein in InterPro IPR013087. Znf_C2H2_type.
SMARTⁱ	View protein in SMART SM00355. ZnF_C2H2. 6 hits.
SUPFAMⁱ	SSF57667. SSF57667. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

L8B7P7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSRRKQGNPQ HLSQRELITP EADHVEAAIL EEDEGLEIEE PSGLGLMVGG 
        60         70         80         90        100
PDPDLLTCGQ CQMNFPLGDI LVFIEHKRKQ CGGSLGACYD KALDKDSPPP 
       110        120        130        140        150
SSRSELRKVS EPVEIGIQVT PDEDDHLLSP TKGICPKQEN IAGPCRPAQL 
       160        170        180        190        200
PAVAPIAASS HPHSSVITSP LRALGALPPC LPLPCCSARP VSGDGTQGEG 
       210        220        230        240        250
QTEAPFGCQC QLSGKDEPSS YICTTCKQPF NSAWFLLQHA QNTHGFRIYL 
       260        270        280        290        300
EPGPASSSLT PRLTIPPPLG PEAVAQSPLM NFLGDSNPFN LLRMTGPILR 
       310        320        330        340        350
DHPGFGEGRL PGTPPLFSPP PRHHLDPHRL SAEEMGLVAQ HPSAFDRVMR 
       360        370        380        390        400
LNPMAIDSPA MDFSRRLREL AGNSSTPPPV SPGRGNPMHR LLNPFQPSPK 
       410        420        430        440        450
SPFLSTPPLP PMPPGGTPPP QPPAKSKSCE FCGKTFKFQS NLIVHRRSHT 
       460        470        480        490        500
GEKPYKCQLC DHACSQASKL KRHMKTHMHK AGSLAGRSDD GLSAASSPEP 
       510        520        530        540        550
GTSELAGEGL KAADGDFRHH ESDPSLGHEP EEEDEEEEEE EEELLLENES 
       560        570        580        590        600
RPESSFSMDS ELSRNRENGG GGVPGVPGAG GGAAKALADE KALVLGKVME 
       610        620        630        640        650
NVGLGALPQY GELLADKQKR GAFLKRAAGG GDAGDDDDAG GCGDAGAGGA 
       660        670        680        690        700
VNGRGGGFAP GTEPFPGLFP RKPAPLPSPG LNSAAKRIKV EKDLELPPAA 
       710        720        730        740        750
LIPSENVYSQ WLVGYAASRH FMKDPFLGFT DARQSPFATS SEHSSENGSL 
       760        770        780        790        800
RFSTPPGDLL DGGLSGRSGT ASGGSTPHLG GPGPGRPSSK EGRRSDTCEY 
       810        820        830        840        850
CGKVFKNCSN LTVHRRSHTG ERPYKCELCN YACAQSSKLT RHMKTHGQIG 
       860        870        880        890 
KEVYRCDICQ MPFSVYSTLE KHMKKWHGEH LLTNDVKIEQ AERS

Length:894

Mass (Da):95,519

Last modified:April 3, 2013 - v1

Checksum:ⁱDF6C467AE2EEC122

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB041218 mRNA. Translation: BAM78282.1. CH471061 Genomic DNA. Translation: EAW81663.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_612808.1. NM_138576.3.
UniGeneⁱ	Hs.709690.

Genome annotation databases

GeneIDⁱ	64919.
KEGGⁱ	hsa:64919.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB041218 mRNA. Translation: BAM78282.1. CH471061 Genomic DNA. Translation: EAW81663.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_612808.1. NM_138576.3.
UniGeneⁱ	Hs.709690.

3D structure databases

SMRⁱ	L8B7P7.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	64919.
KEGGⁱ	hsa:64919.

Organism-specific databases

CTDⁱ	64919.

CTDⁱ

64919.

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
OMAⁱ	DDAGGCG.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G160N.

Miscellaneous databases

ChiTaRSⁱ	BCL11B. human.
GenomeRNAiⁱ	64919.

Gene expression databases

Bgeeⁱ	ENSG00000127152.
ExpressionAtlasⁱ	L8B7P7. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR013087. Znf_C2H2_type.
SMARTⁱ	View protein in SMART SM00355. ZnF_C2H2. 6 hits.
SUPFAMⁱ	SSF57667. SSF57667. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	L8B7P7_HUMAN
Accessionⁱ	L8B7P7Primary (citable) accession number: L8B7P7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 3, 2013
	Last sequence update:	April 3, 2013
	Last modified:	July 5, 2017
	This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - L8B7P7 (L8B7P7_HUMAN)

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ATL1-alpha zinc finger protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - L8B7P7 (L8B7P7_HUMAN)

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ATL1-alpha zinc finger protein

ATL1-alpha

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ