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Protein
Submitted name:

ATL1-alpha zinc finger protein

Gene

ATL1-alpha

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ATL1-alpha zinc finger proteinImported
Submitted name:
B-cell CLL/lymphoma 11B (Zinc finger protein), isoform CRA_bImported
Gene namesi
Name:ATL1-alphaImported
Synonyms:BCL11BImported
ORF Names:hCG_1657560Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiL8B7P7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000349723.

Structurei

3D structure databases

SMRiL8B7P7. Positions 213-250, 425-477, 566-593, 771-875.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini221 – 24424C2H2-typeInterPro annotationAdd
BLAST
Domaini427 – 45428C2H2-typeInterPro annotationAdd
BLAST
Domaini455 – 48228C2H2-typeInterPro annotationAdd
BLAST
Domaini796 – 82328C2H2-typeInterPro annotationAdd
BLAST
Domaini824 – 84623C2H2-typeInterPro annotationAdd
BLAST
Domaini854 – 87724C2H2-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OMAiDDAGGCG.
PhylomeDBiL8B7P7.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L8B7P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRKQGNPQ HLSQRELITP EADHVEAAIL EEDEGLEIEE PSGLGLMVGG
60 70 80 90 100
PDPDLLTCGQ CQMNFPLGDI LVFIEHKRKQ CGGSLGACYD KALDKDSPPP
110 120 130 140 150
SSRSELRKVS EPVEIGIQVT PDEDDHLLSP TKGICPKQEN IAGPCRPAQL
160 170 180 190 200
PAVAPIAASS HPHSSVITSP LRALGALPPC LPLPCCSARP VSGDGTQGEG
210 220 230 240 250
QTEAPFGCQC QLSGKDEPSS YICTTCKQPF NSAWFLLQHA QNTHGFRIYL
260 270 280 290 300
EPGPASSSLT PRLTIPPPLG PEAVAQSPLM NFLGDSNPFN LLRMTGPILR
310 320 330 340 350
DHPGFGEGRL PGTPPLFSPP PRHHLDPHRL SAEEMGLVAQ HPSAFDRVMR
360 370 380 390 400
LNPMAIDSPA MDFSRRLREL AGNSSTPPPV SPGRGNPMHR LLNPFQPSPK
410 420 430 440 450
SPFLSTPPLP PMPPGGTPPP QPPAKSKSCE FCGKTFKFQS NLIVHRRSHT
460 470 480 490 500
GEKPYKCQLC DHACSQASKL KRHMKTHMHK AGSLAGRSDD GLSAASSPEP
510 520 530 540 550
GTSELAGEGL KAADGDFRHH ESDPSLGHEP EEEDEEEEEE EEELLLENES
560 570 580 590 600
RPESSFSMDS ELSRNRENGG GGVPGVPGAG GGAAKALADE KALVLGKVME
610 620 630 640 650
NVGLGALPQY GELLADKQKR GAFLKRAAGG GDAGDDDDAG GCGDAGAGGA
660 670 680 690 700
VNGRGGGFAP GTEPFPGLFP RKPAPLPSPG LNSAAKRIKV EKDLELPPAA
710 720 730 740 750
LIPSENVYSQ WLVGYAASRH FMKDPFLGFT DARQSPFATS SEHSSENGSL
760 770 780 790 800
RFSTPPGDLL DGGLSGRSGT ASGGSTPHLG GPGPGRPSSK EGRRSDTCEY
810 820 830 840 850
CGKVFKNCSN LTVHRRSHTG ERPYKCELCN YACAQSSKLT RHMKTHGQIG
860 870 880 890
KEVYRCDICQ MPFSVYSTLE KHMKKWHGEH LLTNDVKIEQ AERS
Length:894
Mass (Da):95,519
Last modified:April 3, 2013 - v1
Checksum:iDF6C467AE2EEC122
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041218 mRNA. Translation: BAM78282.1.
CH471061 Genomic DNA. Translation: EAW81663.1.
RefSeqiNP_612808.1. NM_138576.3.
UniGeneiHs.709690.

Genome annotation databases

GeneIDi64919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041218 mRNA. Translation: BAM78282.1.
CH471061 Genomic DNA. Translation: EAW81663.1.
RefSeqiNP_612808.1. NM_138576.3.
UniGeneiHs.709690.

3D structure databases

SMRiL8B7P7. Positions 213-250, 425-477, 566-593, 771-875.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000349723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi64919.

Organism-specific databases

CTDi64919.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OMAiDDAGGCG.
PhylomeDBiL8B7P7.

Miscellaneous databases

ChiTaRSiBCL11B. human.
GenomeRNAii64919.

Gene expression databases

ExpressionAtlasiL8B7P7. baseline and differential.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of the human candidate tumor suppressor gene (ATL1-alpha) encoding novel Zinc finger protein."
    Isobe M., Ozawa T.
    Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThymusImported.
  2. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiL8B7P7_HUMAN
AccessioniPrimary (citable) accession number: L8B7P7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: May 11, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.