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Protein

DEAD-box ATP-dependent RNA helicase CshB

Gene

cshB

Organism
Bacillus subtilis BEST7613
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase, RNA-bindingUniRule annotation
Biological processStress responseUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DEAD-box ATP-dependent RNA helicase CshBUniRule annotation (EC:3.6.4.13UniRule annotation)
Gene namesi
Name:cshBUniRule annotationImported
ORF Names:BEST7613_4069Imported
OrganismiBacillus subtilis BEST7613Imported
Taxonomic identifieri1204343 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000011218 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliL8AN93.
SMRiL8AN93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 32Q_MOTIFInterPro annotationAdd BLAST29
Domaini35 – 208Helicase ATP-bindingInterPro annotationAdd BLAST174
Domaini235 – 385Helicase C-terminalInterPro annotationAdd BLAST151

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi4 – 32Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family. CshB subfamily.UniRule annotation

Phylogenomic databases

OrthoDBiPOG091H01ST.

Family and domain databases

HAMAPiMF_01494. DEAD_helicase_CshB. 1 hit.
InterProiView protein in InterPro
IPR030881. CshB.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

L8AN93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKETKFELYE LKPFIIDAVH RLGFYEPTDI QKRLIPAVLK KESVIGQSQT
60 70 80 90 100
GTGKTHAYLL PLLNKIDPAK DVVQVVITAP TRELANQIYQ EALKITQGEE
110 120 130 140 150
GSQIRSKCFI GGTDKQKSID KLKIQPHLVV GTPGRIADLI KEQALSVHKA
160 170 180 190 200
ESLVIDEADL MLDMGFLADV DYIGSRMPED LQMLVFSATI PEKLKPFLKK
210 220 230 240 250
YMENPKYAHV EPKQVTAAKI EHILIPSKHR DKDKLLFDIM SHLNPYLGIV
260 270 280 290 300
FANTKNTADH IAQYLTGKGM KIGLLHGGLT PRERKKVMKQ INDLEFTYII
310 320 330 340 350
ATDLAARGID IKGVSHVINY ELPDDLDFYV HRVGRTARAG SSGQAMTIYE
360 370 380 390 400
LTDEDALVRL EKMGIEFEYL ELEKGEWKKG DDRQRRKKRK KTPNEADEIA
410 420 430
HRLVKKPKKV KPGYKKKMSY EMEKIKKKQR RNQSKKRK
Length:438
Mass (Da):50,027
Last modified:April 3, 2013 - v1
Checksum:iB6D425EF6D433789
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012495 Genomic DNA. Translation: BAM53000.1.

Genome annotation databases

EnsemblBacteriaiBAM53000; BAM53000; BEST7613_4069.
PATRICifig|1148.72.peg.4353.

Similar proteinsi

Entry informationi

Entry nameiL8AN93_BACIU
AccessioniPrimary (citable) accession number: L8AN93
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: June 7, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported