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L8A9N6 (L8A9N6_ENTFC) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. SAAS SAAS020634 HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. SAAS SAAS020634 HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity SAAS SAAS020634 HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
L8A9N6 [UniParc].

Last modified April 3, 2013. Version 1.
Checksum: AFED9871CB7F4735

FASTA19422,347
        10         20         30         40         50         60 
MAQLFFKYGA MNSGKTIEIL KVAHNYEEQN KPVVLMTSGI DTRDGLGVVS SRIGLKRNAM 

        70         80         90        100        110        120 
PIFEETDVFD VIQKMESKPY CVLIDEAQFL KKKHVIAFTR IVDELDIPVM AFGLKNDFRN 

       130        140        150        160        170        180 
ELFEGSKYLL LYADKIEEMK TICWFCHKKA IMNLHYIDGN PVYEGDQVQI GGNEAYYPVC 

       190 
RKHYFHPSMI TEGE 

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References

[1]"Safety of the Surrogate Microorganism Enterococcus faecium NRRL B-2354 for Use in Thermal Process Validation."
Kopit L.M., Kim E.B., Siezen R.J., Harris L.J., Marco M.L.
Appl. Environ. Microbiol. 80:1899-1909(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NRRL B-2354 EMBL AGE30917.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP004063 Genomic DNA. Translation: AGE30917.1.
RefSeqYP_007394978.1. NC_020207.1.

3D structure databases

ProteinModelPortalL8A9N6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAGE30917; AGE30917; M7W_2318.
GeneID14501120.
KEGGefm:M7W_2318.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameL8A9N6_ENTFC
AccessionPrimary (citable) accession number: L8A9N6
Entry history
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: June 11, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)