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L7VAR8

- L7VAR8_MYCL1

UniProt

L7VAR8 - L7VAR8_MYCL1

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium liflandii (strain 128FXT)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei161 – 1611UniRule annotation
    Active sitei593 – 5931UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    Ordered Locus Names:MULP_02690Imported
    OrganismiMycobacterium liflandii (strain 128FXT)Imported
    Taxonomic identifieri459424 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000011157: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    L7VAR8-1 [UniParc]FASTAAdd to Basket

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    MVEVSDTALE PIGDVHRTRI GREATEPMRA DIRLLGAILG DTVREQNGDE    50
    VFELVERARV EAFRVRHSEI DRAEMARMFE GIDIHHAIPI IRAFSHFALL 100
    ANVAEDIHRE RRRSIHVAAG EPPQDSSLAA TYMKLDAAQL DSATIAEALK 150
    GALVSPVITA HPTETRRRTI FETQHRITQL MRLHAEGHTE TDDGRGIEVE 200
    LRRQVLRLWQ TALIRLFRLQ ISDEIEVGLR YYPAALFEVI PQVNAEVRDA 250
    LRARWPDADL LSEPILRPGS WIGGDRDGNP NVTAEVVRLA TGSAAFTALA 300
    HYLAELTALA QELSMSARLI TVTPELATLA DACPAGARPD EPYRRALQVV 350
    RGRLSATAAE ILDQQPQHTL ELGLPPYATA AELRADLDTI DASLHNHGAG 400
    LLADDRLARL REAVRVFGFH LSGLDMRQNS DVHEQVVGEL LAWAGVHPDY 450
    TSLAEAERVE LLAAELSTRR PLIRDGAQLS DLARSELGVL AAAAHAVWTF 500
    GPAAVPNYII SMCRSVSDML EAAVLLKEVG LLDASESEPY CPVGISPLFE 550
    TIEDLHNGAA ILQAMLDLPL YRALVTARGG CQEVMLGYSD SNKDGGYLAA 600
    NWAVYRAELA LVETARKTGI RLRLFHGRGG TVGRGGGPSY QAILAQPPGA 650
    VSGSLRLTEQ GEVIAAKYAE PQMARRNLES LLAATLESTL LDVEGLGNTA 700
    APAYAVLDEV AALAQRAYAE LVHETPGFVE YFKASTPVSE IGALNIGSRP 750
    TSRKPTASIA DLRAIPWVLA WSQSRVMLPG WYGTGSAFEQ WLAAGPESEA 800
    DRLQVLHDLY QRWPFFRSVL SNMAQVMAKS DLELAARYSE LVADETLRRR 850
    VFDKIADEHH RTIAMYKRIT GQDDLLADNP ALARSVFNRF PYLEPLNHLQ 900
    VELLRRYRSG EDDESVLRGI LLTMNGLASA LRNSG 935
    Length:935
    Mass (Da):102,652
    Last modified:April 3, 2013 - v1
    Checksum:iFFEBB13719BD349E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003899 Genomic DNA. Translation: AGC62489.1.
    RefSeqiWP_015355654.1. NC_020133.1.
    YP_007368996.1. NC_020133.1.

    Genome annotation databases

    EnsemblBacteriaiAGC62489; AGC62489; MULP_02690.
    GeneIDi14465467.
    KEGGimli:MULP_02690.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003899 Genomic DNA. Translation: AGC62489.1 .
    RefSeqi WP_015355654.1. NC_020133.1.
    YP_007368996.1. NC_020133.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AGC62489 ; AGC62489 ; MULP_02690 .
    GeneIDi 14465467.
    KEGGi mli:MULP_02690.

    Phylogenomic databases

    KOi K01595.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the frog pathogen Mycobacterium ulcerans ecovar Liflandii."
      Tobias N.J., Doig K.D., Medema M.H., Chen H., Haring V., Moore R., Seemann T., Stinear T.P.
      J. Bacteriol. 195:556-564(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 128FXTImported.

    Entry informationi

    Entry nameiL7VAR8_MYCL1
    AccessioniPrimary (citable) accession number: L7VAR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 3, 2013
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3