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L7TW49

- L7TW49_RIEAN

UniProt

L7TW49 - L7TW49_RIEAN

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Protein

Thymidine kinase

Gene

tdk

Organism
Riemerella anatipestifer RA-CH-2
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei94 – 941Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 288ATPUniRule annotation
Nucleotide bindingi93 – 964ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
ORF Names:G148_0445Imported
OrganismiRiemerella anatipestifer RA-CH-2Imported
Taxonomic identifieri1271752 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella
ProteomesiUP000011132: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

L7TW49-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFLENTINHA KQSGWMEVIC GSMFSGKTEE LIRRLRRAEM AGLNVEIFKP
60 70 80 90 100
KLDTRYSEED VVSHNRNKIR STAVDTPNEI LLLGSNCDVV GIDEAQFFDQ
110 120 130 140 150
GIVEVANQLA NNGVRVVIAG LDMDFKGRPF GPMPYLMATA EYVTKVHAIC
160 170 180 190
KRTGNLANYS MRTSTSQDLV ELGETESYEA VSRRVFVDEF LNKKS
Length:195
Mass (Da):21,906
Last modified:April 3, 2013 - v1
Checksum:iD328D93CBBA44DE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004020 Genomic DNA. Translation: AGC39750.1.
RefSeqiWP_004920607.1. NC_020125.1.
YP_007355444.1. NC_020125.1.

Genome annotation databases

EnsemblBacteriaiAGC39750; AGC39750; G148_0445.
GeneIDi14446812.
KEGGirae:G148_0445.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004020 Genomic DNA. Translation: AGC39750.1 .
RefSeqi WP_004920607.1. NC_020125.1.
YP_007355444.1. NC_020125.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGC39750 ; AGC39750 ; G148_0445 .
GeneIDi 14446812.
KEGGi rae:G148_0445.

Phylogenomic databases

KOi K00857.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics of Riemerella anatipestifer reveals genetic diversity."
    Wang X., Liu W., Zhu D., Yang L., Liu M., Yin S., Wang M., Jia R., Chen S., Sun K., Cheng A., Chen X.
    BMC Genomics 15:479-479(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RA-CH-2Imported.

Entry informationi

Entry nameiL7TW49_RIEAN
AccessioniPrimary (citable) accession number: L7TW49
Entry historyi
Integrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 26, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3