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Protein
Submitted name:

V-crk sarcoma virus CT10 oncogene homolog (Avian)

Gene

CRK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
V-crk sarcoma virus CT10 oncogene homolog (Avian)Imported
Gene namesi
Name:CRKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiL7RT18.
PRIDEiL7RT18.

Expressioni

Gene expression databases

BgeeiENSG00000167193.
ExpressionAtlasiL7RT18. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliL7RT18.
SMRiL7RT18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 118SH2InterPro annotationAdd BLAST106
Domaini132 – 192SH3InterPro annotationAdd BLAST61

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4792. Eukaryota.
ENOG4110574. LUCA.
KOiK04438.
OMAiGSWYWGR.
OrthoDBiEOG091G0JPQ.
PhylomeDBiL7RT18.

Family and domain databases

CDDicd11759. SH3_CRK_C. 1 hit.
cd11758. SH3_CRK_N. 1 hit.
Gene3Di3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR035458. CRK_SH3_C.
IPR035457. CRK_SH3_N.
IPR000980. SH2.
IPR011511. SH3_2.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 1 hit.
SM00326. SH3. 2 hits.
SUPFAMiSSF50044. SSF50044. 3 hits.
SSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

L7RT18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS
60 70 80 90 100
VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL
110 120 130 140 150
LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED
160 170 180 190 200
LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL
210 220 230 240 250
IGGNQEGSHP QPLGGPEPGP YAQPSVNTPL PNLQNGPIYA RVIQKRVPNA
260 270 280 290 300
YDKTALALEV GELVKVTKIN VSGQWEGECN GKRGHFPFTH VRLLDQQNPD

EDFS
Length:304
Mass (Da):33,831
Last modified:April 3, 2013 - v1
Checksum:i4CFBFB65BFC2E265
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX512441 Genomic DNA. Translation: AGC09588.1.
RefSeqiNP_058431.2. NM_016823.3.
UniGeneiHs.461896.

Genome annotation databases

GeneIDi1398.
KEGGihsa:1398.

Similar proteinsi

Entry informationi

Entry nameiL7RT18_HUMAN
AccessioniPrimary (citable) accession number: L7RT18
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: August 30, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.