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Protein

Serine/threonine-protein kinase mTOR

Gene

MDA_GLEAN10024380

Organism
Myotis davidii (David's myotis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase mTORUniRule annotation (EC:2.7.11.1UniRule annotation)
Gene namesi
ORF Names:MDA_GLEAN10024380Imported
OrganismiMyotis davidii (David's myotis)Imported
Taxonomic identifieri225400 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMicrochiropteraVespertilionidaeMyotis
Proteomesi
  • UP000010556 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1428 – 2028FATInterPro annotationAdd BLAST601
Domaini2228 – 2595PI3K/PI4KInterPro annotationAdd BLAST368
Domaini2563 – 2595FATCInterPro annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili709 – 729Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di1.10.1070.11, 1 hit
1.20.120.150, 1 hit
1.25.10.10, 4 hits
1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024585 DUF3385_TOR
IPR003152 FATC_dom
IPR009076 FRB_dom
IPR036738 FRB_sf
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR026683 TOR
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR11139:SF9 PTHR11139:SF9, 1 hit
PfamiView protein in Pfam
PF11865 DUF3385, 1 hit
PF02259 FAT, 1 hit
PF02260 FATC, 1 hit
PF08771 FRB_dom, 1 hit
PF00454 PI3_PI4_kinase, 1 hit
SMARTiView protein in SMART
SM01346 DUF3385, 1 hit
SM01343 FATC, 1 hit
SM00146 PI3Kc, 1 hit
SUPFAMiSSF47212 SSF47212, 1 hit
SSF48371 SSF48371, 5 hits
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS51189 FAT, 1 hit
PS51190 FATC, 1 hit
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

Sequencei

Sequence statusi: Fragment.

L5LPP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GKAGGGAGGL RRWDRRSWRP LRPWPKPHEP RGKMLGTGPA AAAAAAMASS
60 70 80 90 100
NVSILQQFAS GLKSRNEETR AKAAKELQHY VTMELREMSQ EESTRFYDQL
110 120 130 140 150
NHHIFELVSS SDANERKGGI LAIASLIGVE GGNATRIGRF ANYLRNLLPS
160 170 180 190 200
NDPVVMEMAS KAIGRLAMAG DTFTAEYVEF EVKRALEWLG ADRNEGRRHA
210 220 230 240 250
AVLVLRELAI SVPTFFFQQV QPFFDNIFVA VWDPKQAIRE GAVAALRACL
260 270 280 290 300
ILTTQREPKE MQKPQWYRHT FEEAEKGFDE TLAKEKGMNR DDRIHGALLI
310 320 330 340 350
LNELVRISSM EGERLREEME EITQQQLVHD KYCKDLMGFG TKPRHITPFT
360 370 380 390 400
SFQAVQPQPS NALVGLLGYS SHQSLMGFGA SPSPAKSTLV ESRCCRDLME
410 420 430 440 450
EKFDQVCQWV LKCRSSKNSL IQMTILNLLP RLAAFRPSAF TDTQYLQDTM
460 470 480 490 500
NHVLSCVKKE KERTAAFQAL GLLSVAVRSE FKIYLPRVLD IIRAALPPKD
510 520 530 540 550
FAHKRQKAMQ VDATVFTCIS MLARAMGPGI QQDIKELLEP MLAVGLSPAL
560 570 580 590 600
TAVLYDLSRQ IPQLKKDIQD GLLKMLSLVL MHKPLRHPGM PKGLAHQLAS
610 620 630 640 650
PGLTTLPEAS DVGSITLALR TLGSFEFEGH SLTQFVRHCA DHFLNSEHKE
660 670 680 690 700
IRMEAARTCS RLLTPSVHLI SGHAHVVSQT AVQVVADVLS KLLVVGITDP
710 720 730 740 750
DPDIRYCVLA SLDERFDAHL AQAENLQALF VALNDQVFEI RELAICTVGR
760 770 780 790 800
LSSMNPAFVM PFLRKMLIQI LTELEHSGIG RIKEQSARML GHLVSNAPRL
810 820 830 840 850
IRPYMEPILK ALILKLKDPD PDPNPGVINN VLATIGELAQ VSGLEMRKWV
860 870 880 890 900
DELFIIIMDM LQDSSLLAKR QVALWTLGQL VASTGYVVEP YRKYPTLLEV
910 920 930 940 950
LLNFLKTEQN QGTRREAIRV LGLLGALDPY KHKVNIGMID QSRDASAVSL
960 970 980 990 1000
SESKSSQDSS DYSTSEMLVN MGNLPLDEFY PAVSMVALMR IFRDQSLSHH
1010 1020 1030 1040 1050
HTMVVQAITF IFKSLGLKCV QFLPQVMPTF LNVIRVCDGA IREFLFQQLG
1060 1070 1080 1090 1100
MLVSFVKSHI RPYMDEIVTL MREFWVMNTS IQSTIILLIE QIVVALGGEF
1110 1120 1130 1140 1150
KLYLPQLIPH MLRVFMHDNS PGRTVSIKLL AAIQLFGANL DDYLHLLLPP
1160 1170 1180 1190 1200
IVKLFDAPEV PLPSRKAALE TVDRLTESLD FTDYASRIIH PIVRTLDQCP
1210 1220 1230 1240 1250
ELRPTAMDTL SSLVFQLGKK YQIFIPMVNK VLVRHRINHQ RYDVLICRIV
1260 1270 1280 1290 1300
KGYTLADEEE DPLIYQHRML RSGQGDALAS GPVETGPMKK LHVSTINLQK
1310 1320 1330 1340 1350
AADGFLLSPV ELQAWGAARR VSKDDWLEWL RRLSLELLKD SSSPSLRSCW
1360 1370 1380 1390 1400
ALAQAYNPMA RDLFNAAFVS CWSELNEDQQ DELIRSIELA LTSQDIAEVT
1410 1420 1430 1440 1450
QTLLNLAEFM EHSDKGPLPL RDDNGIVLLG ERAAKCRAYA KALHYKELEF
1460 1470 1480 1490 1500
QKGPTPAILE SLISINNKLQ QPEAAAGVLE YAMKHFGELE IQATWYEKLH
1510 1520 1530 1540 1550
EWEDALVAYD KKMDTNKDDP ELMLGRMRCL EALGEWGQLH QQCCEKWTLV
1560 1570 1580 1590 1600
NDETQAKMAR MAAAAAWGLG QWDSMEEYTC MIPRDTHDGA FYRAVLALHQ
1610 1620 1630 1640 1650
DLFSLAQQCI DKARDLLDAE LTAMAGESYS RAYGAMVSCH MLSELEEVIQ
1660 1670 1680 1690 1700
YKLVPERREI IRQIWWERLQ GCQRIVEDWQ KILMVRSLVV NPHEDMRTWL
1710 1720 1730 1740 1750
KYASLCGKSG RLALAHKTLV LLLGVDPSRQ LDHPLPTVHP QVTYAYMKNM
1760 1770 1780 1790 1800
WKSARKIDAF QHMQHFVQTM QQQAQHAIAT EDQQHKQELH KLMARCFLKL
1810 1820 1830 1840 1850
GEWQLNLQGI NESTIPKVLQ YYSAATEHDR SWYKAWHAWA VMNFEAVLHY
1860 1870 1880 1890 1900
KHQNQARDEK KKLRHASGAN ITNTTTASST AAATTTATST EGSNSESEAE
1910 1920 1930 1940 1950
SSENSPTPSP LQKKVAEDLS KTLLMYTVPA VQGFFRSISL SRGNNLQDTL
1960 1970 1980 1990 2000
RVLTLWFDYG HWPDVNEALV EGVKAIQIDT WLQVIPQLIA RIDTPRPLVG
2010 2020 2030 2040 2050
RLIHQLLTDI GRYHPQALIY PLTVASKSTT TARHNAANKI LKNMCEHSNT
2060 2070 2080 2090 2100
LVQQAMMVSE ELIRVAILWH EMWHEGLEEA SRLYFGERNV KGMFEVLEPL
2110 2120 2130 2140 2150
HAMMERGPQT LKETSFNQAY GRDLMEAQEW CRKYMKSGNV KDLTQAWDLY
2160 2170 2180 2190 2200
YHVFRRISKQ LPQLTSLELQ YVSPKLLMCR DLELAVPGTY DPNQPIIRIQ
2210 2220 2230 2240 2250
SIAPSLQVIT SKQRPRKLTL MGSNGHEFVF LLKGHEDLRQ DERVMQLFGL
2260 2270 2280 2290 2300
VNTLLANDPT SLRKNLSIQR YAVIPLSTNS GLIGWVPHCD TLHALIRDYR
2310 2320 2330 2340 2350
EKKKILLNIE HRIMLRMAPD YDHLTLMQKV EVFEHAVNNT AGDDLAKLLW
2360 2370 2380 2390 2400
LKSPSSEVWF DRRTNYTRSL AVMSMVGYIL GLGDRHPSNL MLDRLSGKIL
2410 2420 2430 2440 2450
HIDFGDCFEV AMTREKFPEK IPFRLTRMLT NAMEVTGLDG NYRITCHTVM
2460 2470 2480 2490 2500
EVLREHKDSV MAVLEAFVYD PLLNWRLMDT NTKGNKRSRT RTDSYSAGQS
2510 2520 2530 2540 2550
VEILNGVELG EPAHKKTGTT VPESIHSFIG DGLVKPEALN KKAIEIINRV
2560 2570 2580 2590
RDKLTGRDFS HDDTLDVPTQ VELLIKQATS HENLCQCYIG WCPFW
Length:2,595
Mass (Da):293,945
Last modified:March 6, 2013 - v1
Checksum:iA8611749D1A12D52
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB109639 Genomic DNA Translation: ELK28007.1

Similar proteinsi

Entry informationi

Entry nameiL5LPP5_MYODS
AccessioniPrimary (citable) accession number: L5LPP5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: April 25, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health