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L0SM92

- L0SM92_STREE

UniProt

L0SM92 - L0SM92_STREE

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Protein
Submitted name: Sialidase A (Neuraminidase A)
Gene
nanA, SPN994039_14750
Organism
Streptococcus pneumoniae SPN994039
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
ORF Names:SPN994039_14750Imported
OrganismiStreptococcus pneumoniae SPN994039Imported
Taxonomic identifieri869307 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000006837: Chromosome

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor By similarity SAAS annotations

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliL0SM92.

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0SM92-1 [UniParc]FASTAAdd to Basket

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MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE     50
TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL 100
ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP 150
AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV 200
KPGQWNSVTF TVEKPTAELP KGRVRLYVNG VLSRTSLRSG NFIKDMPDVT 250
HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK 300
KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE 350
RRLHSSDWGD IGMVIRRSED NGKTWGDRVT ITNLRDNPKA SDPSIGSPVN 400
IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY 450
REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL 500
GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF 550
LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR IIYSDDHGKT 600
WHAGEAVNDN RQVDGQKIHS STMNNRRAQN TESTVVQLNN GDVKLFMRGL 650
TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH EGKEYIILSN 700
AGGPKRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI 750
LYEHTEKGQN AYTLSFRKFN WDFLSKDLIS PTEAKVKRTR EMGKGVIGLE 800
FDSEVLVNKA PTLQLANGKT ARFMTQYDTK TLLFTVDSED MGQKVTGLAE 850
GAIESMHNLP VSVAGTKLSN GMNGSEAAVH EVPEYTGPLG TSGEEPAPTV 900
EKPEYTGPLG TSGEEPAPTV EKPEYTGPLG TAGEEAAPTV EKPEFTGGVN 950
GTEPAVHEIA EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA 1000
SLGLTAFFLG LFTLGKKREQ 1020
Length:1,020
Mass (Da):112,843
Last modified:March 6, 2013 - v1
Checksum:iB4BF4F1DDCD3E9E1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312044 Genomic DNA. Translation: CCP35169.1.
RefSeqiWP_014632427.1. NC_021005.1.
YP_007763895.1. NC_021005.1.

Genome annotation databases

EnsemblBacteriaiCCP35169; CCP35169; SPN994039_14750.
GeneIDi15319992.
KEGGispno:SPN994039_14750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312044 Genomic DNA. Translation: CCP35169.1 .
RefSeqi WP_014632427.1. NC_021005.1.
YP_007763895.1. NC_021005.1.

3D structure databases

ProteinModelPortali L0SM92.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCP35169 ; CCP35169 ; SPN994039_14750 .
GeneIDi 15319992.
KEGGi spno:SPN994039_14750.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP994039Imported.
  2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
    Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
    PLoS Genet. 9:e1003868-e1003868(2013)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP994039Imported.

Entry informationi

Entry nameiL0SM92_STREE
AccessioniPrimary (citable) accession number: L0SM92
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: September 3, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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