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L0SLC2

- L0SLC2_STREE

UniProt

L0SLC2 - L0SLC2_STREE

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus pneumoniae SPN034156
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
ORF Names:SPN034156_05750Imported
OrganismiStreptococcus pneumoniae SPN034156Imported
Taxonomic identifieri869303 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008971: Chromosome

Subcellular locationi

Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0SLC2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE
60 70 80 90 100
TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL
110 120 130 140 150
ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP
160 170 180 190 200
AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV
210 220 230 240 250
KPGQWNSVTF TVEKPTAELP KGRVRLYVNG VLSRTSLRSG NFIKDMPDVT
260 270 280 290 300
HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK
310 320 330 340 350
KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE
360 370 380 390 400
RRLHSSDWGD IGMVIRRSED NGKTWGDRVT ITNLRDNPKA SDPSIGSPVN
410 420 430 440 450
IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY
460 470 480 490 500
REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL
510 520 530 540 550
GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF
560 570 580 590 600
LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR VIYSDDHGKT
610 620 630 640 650
WHAGEAVNDN RQVDGQKIHS STMNNERAQN TESTVVQLNN GDVKLFMRGL
660 670 680 690 700
TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH EGKEYIILSN
710 720 730 740 750
AGGPKRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI
760 770 780 790 800
LYEHTEKGQN AYTLSFRKFN WDFLSKDLIS PTEAKVKRTR EMGKGVIGLE
810 820 830 840 850
FDSEVLVNKA PTLQLANGKT ATFLTQYDSK TLLFAVDKED IGQEIIGIAK
860 870 880 890 900
GSIESMHNLP VNLAGARVPG GVNGSKAAVH EVPEFTGGVN GTEPAVHEIA
910 920 930 940 950
EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA SLGLTAFFLG
960
LFTLGKKREQ
Length:960
Mass (Da):106,614
Last modified:March 6, 2013 - v1
Checksum:i860541C3B29526E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312045 Genomic DNA. Translation: CCP36244.1.
RefSeqiYP_007764892.1. NC_021006.1.

Genome annotation databases

EnsemblBacteriaiCCP36244; CCP36244; SPN034156_05750.
GeneIDi15313628.
KEGGispne:SPN034156_05750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ312045 Genomic DNA. Translation: CCP36244.1 .
RefSeqi YP_007764892.1. NC_021006.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCP36244 ; CCP36244 ; SPN034156_05750 .
GeneIDi 15313628.
KEGGi spne:SPN034156_05750.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034156Imported.
  2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
    Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
    PLoS Genet. 9:e1003868-e1003868(2013)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034156Imported.

Entry informationi

Entry nameiL0SLC2_STREE
AccessioniPrimary (citable) accession number: L0SLC2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: November 26, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3