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L0SLC2

- L0SLC2_STREE

UniProt

L0SLC2 - L0SLC2_STREE

Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus pneumoniae SPN034156
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 10 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-sialidase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase A (Neuraminidase A)Imported
    Gene namesi
    Name:nanAImported
    ORF Names:SPN034156_05750Imported
    OrganismiStreptococcus pneumoniae SPN034156Imported
    Taxonomic identifieri869303 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000008971: Chromosome

    Subcellular locationi

    Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

    GO - Cellular componenti

    1. cell wall Source: UniProtKB-SubCell
    2. extracellular region Source: UniProtKB-KW
    3. membrane Source: InterPro

    Keywords - Cellular componenti

    SecretedSAAS annotation

    Family & Domainsi

    Phylogenomic databases

    KOiK01186.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR005877. YSIRK_signal_dom.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PfamiPF02973. Sialidase. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view]
    SMARTiSM00282. LamG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    L0SLC2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE    50
    TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL 100
    ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP 150
    AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV 200
    KPGQWNSVTF TVEKPTAELP KGRVRLYVNG VLSRTSLRSG NFIKDMPDVT 250
    HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK 300
    KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE 350
    RRLHSSDWGD IGMVIRRSED NGKTWGDRVT ITNLRDNPKA SDPSIGSPVN 400
    IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY 450
    REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL 500
    GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF 550
    LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR VIYSDDHGKT 600
    WHAGEAVNDN RQVDGQKIHS STMNNERAQN TESTVVQLNN GDVKLFMRGL 650
    TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH EGKEYIILSN 700
    AGGPKRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI 750
    LYEHTEKGQN AYTLSFRKFN WDFLSKDLIS PTEAKVKRTR EMGKGVIGLE 800
    FDSEVLVNKA PTLQLANGKT ATFLTQYDSK TLLFAVDKED IGQEIIGIAK 850
    GSIESMHNLP VNLAGARVPG GVNGSKAAVH EVPEFTGGVN GTEPAVHEIA 900
    EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA SLGLTAFFLG 950
    LFTLGKKREQ 960
    Length:960
    Mass (Da):106,614
    Last modified:March 6, 2013 - v1
    Checksum:i860541C3B29526E4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312045 Genomic DNA. Translation: CCP36244.1.
    RefSeqiYP_007764892.1. NC_021006.1.

    Genome annotation databases

    EnsemblBacteriaiCCP36244; CCP36244; SPN034156_05750.
    GeneIDi15313628.
    KEGGispne:SPN034156_05750.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FQ312045 Genomic DNA. Translation: CCP36244.1 .
    RefSeqi YP_007764892.1. NC_021006.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CCP36244 ; CCP36244 ; SPN034156_05750 .
    GeneIDi 15313628.
    KEGGi spne:SPN034156_05750.

    Phylogenomic databases

    KOi K01186.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    IPR005877. YSIRK_signal_dom.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    Pfami PF02973. Sialidase. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view ]
    SMARTi SM00282. LamG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SNP034156Imported.
    2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
      Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
      PLoS Genet. 9:e1003868-e1003868(2013)
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SNP034156Imported.

    Entry informationi

    Entry nameiL0SLC2_STREE
    AccessioniPrimary (citable) accession number: L0SLC2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 10 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3