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L0SLC2

- L0SLC2_STREE

UniProt

L0SLC2 - L0SLC2_STREE

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Protein
Submitted name: Sialidase A (Neuraminidase A)
Gene
nanA, SPN034156_05750
Organism
Streptococcus pneumoniae SPN034156
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
ORF Names:SPN034156_05750Imported
OrganismiStreptococcus pneumoniae SPN034156Imported
Taxonomic identifieri869303 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008971: Chromosome

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor By similarity SAAS annotations

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0SLC2-1 [UniParc]FASTAAdd to Basket

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MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE    50
TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL 100
ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP 150
AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV 200
KPGQWNSVTF TVEKPTAELP KGRVRLYVNG VLSRTSLRSG NFIKDMPDVT 250
HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK 300
KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE 350
RRLHSSDWGD IGMVIRRSED NGKTWGDRVT ITNLRDNPKA SDPSIGSPVN 400
IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY 450
REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL 500
GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF 550
LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR VIYSDDHGKT 600
WHAGEAVNDN RQVDGQKIHS STMNNERAQN TESTVVQLNN GDVKLFMRGL 650
TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH EGKEYIILSN 700
AGGPKRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI 750
LYEHTEKGQN AYTLSFRKFN WDFLSKDLIS PTEAKVKRTR EMGKGVIGLE 800
FDSEVLVNKA PTLQLANGKT ATFLTQYDSK TLLFAVDKED IGQEIIGIAK 850
GSIESMHNLP VNLAGARVPG GVNGSKAAVH EVPEFTGGVN GTEPAVHEIA 900
EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA SLGLTAFFLG 950
LFTLGKKREQ 960
Length:960
Mass (Da):106,614
Last modified:March 6, 2013 - v1
Checksum:i860541C3B29526E4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312045 Genomic DNA. Translation: CCP36244.1.
RefSeqiYP_007764892.1. NC_021006.1.

Genome annotation databases

EnsemblBacteriaiCCP36244; CCP36244; SPN034156_05750.
GeneIDi15313628.
KEGGispne:SPN034156_05750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312045 Genomic DNA. Translation: CCP36244.1 .
RefSeqi YP_007764892.1. NC_021006.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCP36244 ; CCP36244 ; SPN034156_05750 .
GeneIDi 15313628.
KEGGi spne:SPN034156_05750.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034156Imported.
  2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
    Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
    PLoS Genet. 9:e1003868-e1003868(2013)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034156Imported.

Entry informationi

Entry nameiL0SLC2_STREE
AccessioniPrimary (citable) accession number: L0SLC2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: September 3, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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