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L0SJ67 (L0SJ67_STREE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595 EMBL CCP34663.1
ORF Names:SPN994039_09690 EMBL CCP34663.1
OrganismStreptococcus pneumoniae SPN994039 [Complete proteome] EMBL CCP34663.1
Taxonomic identifier869307 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length898 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1381 By similarity HAMAP-Rule MF_00595
Active site5611 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
L0SJ67 [UniParc].

Last modified March 6, 2013. Version 1.
Checksum: F154EF32ED90E22E

FASTA898103,259
        10         20         30         40         50         60 
MSLQKLENYS NKSVVKEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST QEDYQGLNRL 

        70         80         90        100        110        120 
VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN IDQDYLGKLS TTIKLVAEKE 

       130        140        150        160        170        180 
NAVEILEHLN VVPVLTAHPT QVQRKSMLDL TNHIHSLLRK YRDVKLGLIN KDKWHNDLRR 

       190        200        210        220        230        240 
YIEIIMQTDM IREKKLKVTN EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP 

       250        260        270        280        290        300 
ITMGMWIGGD RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 

       310        320        330        340        350        360 
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET ANDFYKDLIA 

       370        380        390        400        410        420 
IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD SSVYEACVAE LLKSAGIHSR 

       430        440        450        460        470        480 
YSELSEEEKC DLLLKELEED PRILSATHAE KSELLAKELA IFKTARVLKD KLGDDVIRQT 

       490        500        510        520        530        540 
IISHATSLSD MLELAILLKE VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK 

       550        560        570        580        590        600 
KWIDSRNNYQ EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 

       610        620        630        640        650        660 
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV SAAINRMITQ 

       670        680        690        700        710        720 
KKSDTNTPNR YEAIMDQVVD RSYDIYRDLV FGNEHFYDYF FESSPIKAIS SFNIGSRPAA 

       730        740        750        760        770        780 
RKTITEIGGL RAIPWVFSWS QSRVMFPGWY GVGSSFKEFI NKNPENIAIL RDMYQNWPFF 

       790        800        810        820        830        840 
QSLLSNVDMV LSKSNMNIAF EYAKLCEDEQ VKAIYETILN EWQVTKNVIL AIEGHDELLA 

       850        860        870        880        890 
DNPYLKASLD YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG 

« Hide

References

[1]"Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species."
Donati C., Hiller N.L., Tettelin H., Muzzi A., Croucher N.J., Angiuoli S.V., Oggioni M., Dunning Hotopp J.C., Hu F.Z., Riley D., Covacci A., Mitchell T.J., Bentley S.D., Kilian M., Ehrlich G.D., Rappuoli R., Moxon E.R., Masignani V.
Genome Biol. 11:R107-R107(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SNP994039 EMBL CCP34663.1.
[2]"Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
PLoS Genet. 9:e1003868-e1003868(2013)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SNP994039 EMBL CCP34663.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FQ312044 Genomic DNA. Translation: CCP34663.1.
RefSeqYP_007763438.1. NC_021005.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCCP34663; CCP34663; SPN994039_09690.
GeneID15319454.
KEGGspno:SPN994039_09690.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameL0SJ67_STREE
AccessionPrimary (citable) accession number: L0SJ67
Entry history
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: June 11, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)