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L0SD23

- L0SD23_STREE

UniProt

L0SD23 - L0SD23_STREE

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Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

nanA

Organism
Streptococcus pneumoniae SPN034183
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
Name:nanAImported
ORF Names:SPN034183_14850Imported
OrganismiStreptococcus pneumoniae SPN034183Imported
Taxonomic identifieri869304 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008970: Chromosome

Subcellular locationi

Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliL0SD23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0SD23-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNRSVQERKC RYSIRKLSVG AVSMIVGAVV FGTSPVLAQE GASEQPLANE
60 70 80 90 100
TQLSGESSTL TDTEKSQPSS ETELSGNKQE QERKDKQEEK IPRDYYARDL
110 120 130 140 150
ENVETVIEKE DVETNASNGQ RVDLSSELDK LKKLENATVH MEFKPDAKAP
160 170 180 190 200
AFYNLFSVSS ATKKDEYFTM AVYNNTATLE GRGSDGKQFY NNYNDAPLKV
210 220 230 240 250
KPGQWNSVTF TVEKPTAELP KGRVRLYVNG VLSRTSLRSG NFIKDMPDVT
260 270 280 290 300
HVQIGATKRA NNTVWGSNLQ IRNLTVYNRA LTPEEVQKRS QLFKRSDLEK
310 320 330 340 350
KLPEGAALTE KTDIFESGRN GKPNKDGIKS YRIPALLKTD KGTLIAGADE
360 370 380 390 400
RRLHSSDWGD IGMVIRRSED NGKTWGDRVT ITNLRDNPKA SDPSIGSPVN
410 420 430 440 450
IDMVLVQDPE TKRIFSIYDM FPEGKGIFGM SSQKEEAYKK IDGKTYQILY
460 470 480 490 500
REGEKGAYTI RENGTVYTPD GKATDYRVVV DPVKPAYSDK GDLYKGNQLL
510 520 530 540 550
GNIYFTTNKT SPFRIAKDSY LWMSYSDDDG KTWSAPQDIT PMVKADWMKF
560 570 580 590 600
LGVGPGTGIV LRNGPHKGRI LIPVYTTNNV SHLNGSQSSR IIYSDDHGKT
610 620 630 640 650
WHAGEAVNDN RQVDGQKIHS STMNNRRAQN TESTVVQLNN GDVKLFMRGL
660 670 680 690 700
TGDLQVATSK DGGVTWEKDI KRYPQVKDVY VQMSAIHTMH EGKEYIILSN
710 720 730 740 750
AGGPKRENGM VHLARVEENG ELTWLKHNPI QKGEFAYNSL QELGNGEYGI
760 770 780 790 800
LYEHTEKGQN AYTLSFRKFN WDFLSKDLIS PTEAKVKRTR EMGKGVIGLE
810 820 830 840 850
FDSEVLVNKA PTLQLANGKT ARFMTQYDTK TLLFTVDSED MGQKVTGLAE
860 870 880 890 900
GAIESMHNLP VSVAGTKLSN GMNGSEAAVH EVPEYTGPLG TSGEEPAPTV
910 920 930 940 950
EKPEYTGPLG TSGEEPAPTV EKPEYTGPLG TAGEEAAPTV EKPEFTGGVN
960 970 980 990 1000
GTEPAVHEIA EYKGSDSLVT LTTKEDYTYK APLAQQALPE TGNKESDLLA
1010 1020
SLGLTAFFLG LFTLGKKREQ
Length:1,020
Mass (Da):112,843
Last modified:March 6, 2013 - v1
Checksum:iB4BF4F1DDCD3E9E1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312043 Genomic DNA. Translation: CCP33195.1.
RefSeqiYP_007815043.1. NC_021028.1.

Genome annotation databases

EnsemblBacteriaiCCP33195; CCP33195; SPN034183_14850.
GeneIDi15315767.
KEGGispnu:SPN034183_14850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312043 Genomic DNA. Translation: CCP33195.1 .
RefSeqi YP_007815043.1. NC_021028.1.

3D structure databases

ProteinModelPortali L0SD23.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCP33195 ; CCP33195 ; SPN034183_14850 .
GeneIDi 15315767.
KEGGi spnu:SPN034183_14850.

Phylogenomic databases

KOi K01186.

Family and domain databases

Gene3Di 2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
PANTHERi PTHR10628. PTHR10628. 1 hit.
Pfami PF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SMARTi SM00282. LamG. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034183Imported.
  2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
    Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
    PLoS Genet. 9:e1003868-e1003868(2013)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034183Imported.

Entry informationi

Entry nameiL0SD23_STREE
AccessioniPrimary (citable) accession number: L0SD23
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: October 29, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3