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L0SBC6

- L0SBC6_STREE

UniProt

L0SBC6 - L0SBC6_STREE

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, SPN034183_09790
Organism
Streptococcus pneumoniae SPN034183
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei561 – 5611 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:SPN034183_09790Imported
OrganismiStreptococcus pneumoniae SPN034183Imported
Taxonomic identifieri869304 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000008970: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0SBC6-1 [UniParc]FASTAAdd to Basket

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MSLQKLENYS NKSVVKEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST    50
QEDYQGLNRL VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN 100
IDQDYLGKLS TTIKLVAEKE NAVEILEHLN VVPVLTAHPT QVQRKSMLDL 150
TNHIHSLLRK YRDVKLGLIN KDKWHNNLRR YIEIIMQTDM IREKKLKVTN 200
EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP ITMGMWIGGD 250
RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 300
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET 350
ANDFYKDLIA IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD 400
SSVYEACVAE LLKSAGIHSR YSELSEEEKC DLLLKELEED PRILSATHAE 450
KSELLAKELA IFKTARVLKD KLGDDVIRQT IISHATSLSD MLELAILLKE 500
VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK KWIDSRNNYQ 550
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 600
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV 650
SAAINRMITQ KKSDTNTPNR YEAIMDQVVD RSYDIYRDLV FGNEHFYDYF 700
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY 750
GVGSSFKEFI NKNPENIAIL RDMYQNWPFF QSLLSNVDMV LSKSNMNIAF 800
EYAKLCEDEQ VKAIYETILN EWQVTKNVIL AIEGHDELLA DNPYLKASLD 850
YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG 898
Length:898
Mass (Da):103,258
Last modified:March 6, 2013 - v1
Checksum:iF675011EA89F8E09
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312043 Genomic DNA. Translation: CCP32689.1.
RefSeqiWP_015545702.1. NC_021028.1.
YP_007814587.1. NC_021028.1.

Genome annotation databases

EnsemblBacteriaiCCP32689; CCP32689; SPN034183_09790.
GeneIDi15315670.
KEGGispnu:SPN034183_09790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FQ312043 Genomic DNA. Translation: CCP32689.1 .
RefSeqi WP_015545702.1. NC_021028.1.
YP_007814587.1. NC_021028.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCP32689 ; CCP32689 ; SPN034183_09790 .
GeneIDi 15315670.
KEGGi spnu:SPN034183_09790.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034183Imported.
  2. "Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection."
    Croucher N.J., Mitchell A.M., Gould K.A., Inverarity D., Barquist L., Feltwell T., Fookes M.C., Harris S.R., Dordel J., Salter S.J., Browall S., Zemlickova H., Parkhill J., Normark S., Henriques-Normark B., Hinds J., Mitchell T.J., Bentley S.D.
    PLoS Genet. 9:e1003868-e1003868(2013)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SNP034183Imported.

Entry informationi

Entry nameiL0SBC6_STREE
AccessioniPrimary (citable) accession number: L0SBC6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: September 3, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi