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L0L8F7

- L0L8F7_HUMAN

UniProt

L0L8F7 - L0L8F7_HUMAN

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Protein
Submitted name: MHC class I chain-related protein A
Gene
HLA-MICA
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation Source: InterPro
  2. immune response Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I chain-related protein AImported
Gene namesi
Name:HLA-MICAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiL0L8F7.

Structurei

3D structure databases

ProteinModelPortaliL0L8F7.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

L0L8F7-1 [UniParc]FASTAAdd to Basket

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PHSLRYNLTV LSWDGSVQSG FLAEVHLDGQ PFLRYDRQKC RAKPQGQWAE    50
DVLGNKTWDR ETRDLTGNGK DLRMTLAHIK DQKEGLHSLQ EIRVCEIHED 100
NSTRSSQHFY YDGELFLSQN LETEEWTVPQ SSRAQTLAMN VRNFLKEDAM 150
KTKTHYHAMH ADCLQELRRY LESGVVLRRT VPPMVNVTRS EASEGNITVT 200
CRASSFYPRN IILTWRQDGV SLSHDTQQWG DVLPDGNGTY QTWVATRICR 250
GEEQRFTCYM EHSGNHSTHP VPSGKVLVLQ SHWQTFHVSA VAAGCCYFCY 300
YYFLCPLL 308
Length:308
Mass (Da):35,495
Last modified:March 6, 2013 - v1
Checksum:i3E2D18DA50FB2D46
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX961659 Genomic DNA. Translation: AGB57986.1.
UniGeneiHs.130838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JX961659 Genomic DNA. Translation: AGB57986.1 .
UniGenei Hs.130838.

3D structure databases

ProteinModelPortali L0L8F7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

ArrayExpressi L0L8F7.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Du Z., Jiao S., Liu X., Wu Z.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Identification of a novel allele MICA*008:05 by sequence-based typing."
    Du Z.H., Jiao S.X., Du B., Liu X.H., Wu Z.J.
    Tissue Antigens 82:217-218(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiL0L8F7_HUMAN
AccessioniPrimary (citable) accession number: L0L8F7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: July 9, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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