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Protein
Submitted name:

MHC class I chain-related protein A

Gene

HLA-MICA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation Source: InterPro
  2. immune response Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I chain-related protein AImported
Gene namesi
Name:HLA-MICAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiL0L8F7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliL0L8F7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

L0L8F7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
PHSLRYNLTV LSWDGSVQSG FLAEVHLDGQ PFLRYDRQKC RAKPQGQWAE
60 70 80 90 100
DVLGNKTWDR ETRDLTGNGK DLRMTLAHIK DQKEGLHSLQ EIRVCEIHED
110 120 130 140 150
NSTRSSQHFY YDGELFLSQN LETEEWTVPQ SSRAQTLAMN VRNFLKEDAM
160 170 180 190 200
KTKTHYHAMH ADCLQELRRY LESGVVLRRT VPPMVNVTRS EASEGNITVT
210 220 230 240 250
CRASSFYPRN IILTWRQDGV SLSHDTQQWG DVLPDGNGTY QTWVATRICR
260 270 280 290 300
GEEQRFTCYM EHSGNHSTHP VPSGKVLVLQ SHWQTFHVSA VAAGCCYFCY

YYFLCPLL
Length:308
Mass (Da):35,495
Last modified:March 6, 2013 - v1
Checksum:i3E2D18DA50FB2D46
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX961659 Genomic DNA. Translation: AGB57986.1.
UniGeneiHs.130838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX961659 Genomic DNA. Translation: AGB57986.1.
UniGeneiHs.130838.

3D structure databases

ProteinModelPortaliL0L8F7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

ExpressionAtlasiL0L8F7. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Du Z., Jiao S., Liu X., Wu Z.
    Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Identification of a novel allele MICA*008:05 by sequence-based typing."
    Du Z.H., Jiao S.X., Du B., Liu X.H., Wu Z.J.
    Tissue Antigens 82:217-218(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiL0L8F7_HUMAN
AccessioniPrimary (citable) accession number: L0L8F7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: October 29, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.