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L0L8F7

- L0L8F7_HUMAN

UniProt

L0L8F7 - L0L8F7_HUMAN

Protein
Submitted name:

MHC class I chain-related protein A

Gene

HLA-MICA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 10 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. antigen processing and presentation Source: InterPro
    2. immune response Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class I chain-related protein AImported
    Gene namesi
    Name:HLA-MICAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Expressioni

    Gene expression databases

    ArrayExpressiL0L8F7.

    Structurei

    3D structure databases

    ProteinModelPortaliL0L8F7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view]
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    L0L8F7-1 [UniParc]FASTAAdd to Basket

    « Hide

    PHSLRYNLTV LSWDGSVQSG FLAEVHLDGQ PFLRYDRQKC RAKPQGQWAE    50
    DVLGNKTWDR ETRDLTGNGK DLRMTLAHIK DQKEGLHSLQ EIRVCEIHED 100
    NSTRSSQHFY YDGELFLSQN LETEEWTVPQ SSRAQTLAMN VRNFLKEDAM 150
    KTKTHYHAMH ADCLQELRRY LESGVVLRRT VPPMVNVTRS EASEGNITVT 200
    CRASSFYPRN IILTWRQDGV SLSHDTQQWG DVLPDGNGTY QTWVATRICR 250
    GEEQRFTCYM EHSGNHSTHP VPSGKVLVLQ SHWQTFHVSA VAAGCCYFCY 300
    YYFLCPLL 308
    Length:308
    Mass (Da):35,495
    Last modified:March 6, 2013 - v1
    Checksum:i3E2D18DA50FB2D46
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX961659 Genomic DNA. Translation: AGB57986.1.
    UniGeneiHs.130838.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX961659 Genomic DNA. Translation: AGB57986.1 .
    UniGenei Hs.130838.

    3D structure databases

    ProteinModelPortali L0L8F7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi L0L8F7.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view ]
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Du Z., Jiao S., Liu X., Wu Z.
      Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Identification of a novel allele MICA*008:05 by sequence-based typing."
      Du Z.H., Jiao S.X., Du B., Liu X.H., Wu Z.J.
      Tissue Antigens 82:217-218(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiL0L8F7_HUMAN
    AccessioniPrimary (citable) accession number: L0L8F7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 10 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.