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L0KJQ9

- L0KJQ9_MESAW

UniProt

L0KJQ9 - L0KJQ9_MESAW

Protein

Thymidine kinase

Gene

tdk

Organism
Mesorhizobium australicum (strain LMG 24608 / HAMBI 3006 / WSM2073)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei88 – 881Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi9 – 168ATPUniRule annotation
    Nucleotide bindingi87 – 904ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    Ordered Locus Names:Mesau_02155Imported
    OrganismiMesorhizobium australicum (strain LMG 24608 / HAMBI 3006 / WSM2073)Imported
    Taxonomic identifieri754035 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000010998: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    L0KJQ9-1 [UniParc]FASTAAdd to Basket

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    MAKLYFHYAT MNAGKTTMLL QASYNYRERG MTTMLFVAGH YRKGDTGLIS    50
    SRIGLETEAE MFRDGDDLFA RVAEHHQHTA VHCIFVDEAQ FLEEEQVWQL 100
    ARIADRLNIP VMCYGLRTDF QGKLFPGSRA LLAIADDLRE VRTICRCGRK 150
    ATMVVRLGPD GKVARQGEQV AIGKDVYVSL AAGIGKRKWA ARHLTTSSAS 200
    SAAECGSLRR RRG 213
    Length:213
    Mass (Da):23,802
    Last modified:March 6, 2013 - v1
    Checksum:iDEC49AD2DED9F2F8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003358 Genomic DNA. Translation: AGB44594.1.
    RefSeqiYP_007303970.1. NC_019973.1.

    Genome annotation databases

    EnsemblBacteriaiAGB44594; AGB44594; Mesau_02155.
    GeneIDi14399705.
    KEGGimam:Mesau_02155.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003358 Genomic DNA. Translation: AGB44594.1 .
    RefSeqi YP_007303970.1. NC_019973.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AGB44594 ; AGB44594 ; Mesau_02155 .
    GeneIDi 14399705.
    KEGGi mam:Mesau_02155.

    Phylogenomic databases

    KOi K00857.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Mesorhizobium australicum WSM2073."
      Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Gu W., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Reeve W.G., Howieson J.G.
      , Tiwari R.P., O'Hara G.W., Atkins C.A., Ronson C.W., Nandasena K.G., Woyke T.
      Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LMG 24608 / HAMBI 3006 / WSM2073Imported.

    Entry informationi

    Entry nameiL0KJQ9_MESAW
    AccessioniPrimary (citable) accession number: L0KJQ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3