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L0JDK6

- L0JDK6_PREDD

UniProt

L0JDK6 - L0JDK6_PREDD

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Protein

Thymidine kinase

Gene

tdk

Organism
Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772) (Mitsuokella dentalis)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931Proton acceptorUniRule annotation
Metal bindingi149 – 1491ZincUniRule annotation
Metal bindingi152 – 1521ZincUniRule annotation
Metal bindingi181 – 1811ZincUniRule annotation
Metal bindingi184 – 1841ZincUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 278ATPUniRule annotation
Nucleotide bindingi92 – 954ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Prede_1623Imported
OrganismiPrevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772) (Mitsuokella dentalis)Imported
Taxonomic identifieri908937 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella
ProteomesiUP000010862: Chromosome 2

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

L0JDK6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMENLTGEAH RPGRIEVVCG SMFSGKTEEL IRRLKRAQFA RQNVEIFKPA
60 70 80 90 100
LDTRYSEINV VSHDNNAIHS TPVDNAETIL RLSAGHEVVG IDEAQFLDDK
110 120 130 140 150
LVEVCNAMAN KGIRVIVAGL DMDYLGVPFG PIPALCAVAD EVTKVHAICV
160 170 180 190 200
KCGALAYASH RLVHNDAQVM LGEKMEYEPL CRSCFQKALE EDRRNAQSRS

LFEHVAP
Length:207
Mass (Da):22,932
Last modified:March 6, 2013 - v1
Checksum:i32472F2179630795
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003369 Genomic DNA. Translation: AGB28928.1.
RefSeqiWP_015310358.1. NC_019968.1.
YP_007296434.1. NC_019968.1.

Genome annotation databases

EnsemblBacteriaiAGB28928; AGB28928; Prede_1623.
GeneIDi14388964.
KEGGipdt:Prede_1623.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003369 Genomic DNA. Translation: AGB28928.1 .
RefSeqi WP_015310358.1. NC_019968.1.
YP_007296434.1. NC_019968.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGB28928 ; AGB28928 ; Prede_1623 .
GeneIDi 14388964.
KEGGi pdt:Prede_1623.

Phylogenomic databases

KOi K00857.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772Imported.

Entry informationi

Entry nameiL0JDK6_PREDD
AccessioniPrimary (citable) accession number: L0JDK6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: November 26, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3