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L0IXX6

- L0IXX6_MYCSM

UniProt

L0IXX6 - L0IXX6_MYCSM

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium smegmatis JS623
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei161 – 1611UniRule annotation
    Active sitei593 – 5931UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    ORF Names:Mycsm_02866Imported
    OrganismiMycobacterium smegmatis JS623Imported
    Taxonomic identifieri710686 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000010844: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    L0IXX6-1 [UniParc]FASTAAdd to Basket

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    MAEGPDVALA PIGSVRRTQV GREATEPMRE DIRLLGTILG DTVREQNGEE    50
    VFDLVERARV ESFRVRRSEI DRAELARMFD GIDIHQAIPV IRAFSHFALL 100
    ANVAEDIHRE RRRAVHVAAG EPPQNSSLAA TYLKLDSAEL DSATVADALR 150
    GALVAPVITA HPTETRRRTV FDTQHRITEL MRLRLHGQTE TDDGRNINLE 200
    LRRHIFTLWQ TALIRLSRLK IQDEIKTGLR YYQAAFLEVI PKVNAEVRTA 250
    LQARWPEADL LELPILRPGS WIGGDRDGNP NVTADVVRQA TGRASYTAFE 300
    HYFTEISALE QELSMSARLV KVSDDLAALA DKCHEPARAD EPYRRALRVI 350
    HGRLTATAGE ILDSQPEHEL DLGLQRYVTP AELLADLDVI DHSLRSNGSG 400
    VLADDRLAQL REAVRVFGFH LSGLDLRQNS DVHEEVVAEL LAWAGVHADY 450
    QSLSEPERVE LLAAELATRR PLTKDDAELS ELARKELDIV AAAARAVHVY 500
    GPHAIPNYII SMCQSVSDML EAAILLKEVG LLDASGDEPY APVGIVPLFE 550
    TIDDLQRGSS ILEAVLDLPL YRAVVTARGD SQEVMLGYSD SNKDGGYLAA 600
    NWALYRAELD LVESARKTGI RLRLFHGRGG TVGRGGGPSY DAILAQPPGA 650
    VNGSLRITEQ GEVIAAKYAE PRVAHRNLET LLAATLEATL LDVEGLGDAA 700
    EPAYEVLDEL AARAQRAYAE LVHVTPGFVE YFKASTPVSE IGALNIGSRP 750
    TSRKPTTSIS DLRAIPWVLA WSQSRVMLPG WYGTGAAFEG WIAEGDGRLE 800
    VLQDLYHRWP FFRTVLSNMA QVLSKSDMGL AARYSELVED EALRQRVFDK 850
    IVDEHDRTIR MHKLITGQDD LLADNPALAR SVFNRFPYLE PLNHLQVELL 900
    RRYRSGDDDE LVQRGILLTM SGLATALRNS G 931
    Length:931
    Mass (Da):103,045
    Last modified:March 6, 2013 - v1
    Checksum:i46ADB222FDF7717E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003078 Genomic DNA. Translation: AGB23192.1.
    RefSeqiWP_015306771.1. NC_019966.1.
    YP_007292597.1. NC_019966.1.

    Genome annotation databases

    EnsemblBacteriaiAGB23192; AGB23192; Mycsm_02866.
    GeneIDi14385197.
    KEGGimsa:Mycsm_02866.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003078 Genomic DNA. Translation: AGB23192.1 .
    RefSeqi WP_015306771.1. NC_019966.1.
    YP_007292597.1. NC_019966.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AGB23192 ; AGB23192 ; Mycsm_02866 .
    GeneIDi 14385197.
    KEGGi msa:Mycsm_02866.

    Phylogenomic databases

    KOi K01595.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Mycobacterium smegmatis JS623."
      US DOE Joint Genome Institute
      Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.
      , Rutledge P., Paulsen I., Coleman N., Woyke T.
      Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: JS623Imported.

    Entry informationi

    Entry nameiL0IXX6_MYCSM
    AccessioniPrimary (citable) accession number: L0IXX6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3