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L0HDG7

- L0HDG7_METFS

UniProt

L0HDG7 - L0HDG7_METFS

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 9 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:Metfor_1008Imported
    OrganismiMethanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP)Imported
    Taxonomic identifieri593750 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
    ProteomesiUP000010824: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    L0HDG7-1 [UniParc]FASTAAdd to Basket

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    MSTQHPDNVH VPFFAETSEL GGEDEVKEAY YIYSHLGCHE QMWDCEGKEV    50
    DNFVVKKLLT TYSPFFADNI LGKDIFLTLR VPNPHIEKAE AKILLETLES 100
    IPRSFDVARI FYKNDIPPIF EVILPMTDTH TAIDNIYQYY ADFVIGKQFK 150
    RLGGRDTTIA DWIGTFSPKH INVIPLFEDQ TSMLSAHTTV GRYILDKHLP 200
    YQRVFLARSD PAMNYGLVSA VLLNKIALAN LHRLQEETGV PVYPVIGVGS 250
    APFRGNLRPD TVDRVSAEYP SAYTFTIQSA FKYDYPPDEA RNAVRALESR 300
    AVSTPHRVDE TQCLQIMERY TEAYIRELIP LSDIINRIAG HIPGRRKRKL 350
    HIGLFGYSRN TGGMKLPRAI TFTAALYSIG IPPEILGLSA LSDRDLDFVR 400
    RIYVNFDRDL CDAARYLNPD SPYLGEGMKD ALLSITGDRI NDDHRQATEN 450
    ILRALRESRT AEIQSDILHA ANIRKFLG 478
    Length:478
    Mass (Da):54,217
    Last modified:March 6, 2013 - v1
    Checksum:iC286F8F731AEB71F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003167 Genomic DNA. Translation: AGB02060.1.
    RefSeqiYP_007248567.1. NC_019943.1.

    Genome annotation databases

    EnsemblBacteriaiAGB02060; AGB02060; Metfor_1008.
    GeneIDi14310321.
    KEGGimfo:Metfor_1008.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003167 Genomic DNA. Translation: AGB02060.1 .
    RefSeqi YP_007248567.1. NC_019943.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AGB02060 ; AGB02060 ; Metfor_1008 .
    GeneIDi 14310321.
    KEGGi mfo:Metfor_1008.

    Phylogenomic databases

    KOi K01595.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 22288 / NBRC 105244 / SMSPImported.

    Entry informationi

    Entry nameiL0HDG7_METFS
    AccessioniPrimary (citable) accession number: L0HDG7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 9 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3