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L0HDG7

- L0HDG7_METFS

UniProt

L0HDG7 - L0HDG7_METFS

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Metfor_1008Imported
OrganismiMethanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP)Imported
Taxonomic identifieri593750 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
ProteomesiUP000010824: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

L0HDG7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTQHPDNVH VPFFAETSEL GGEDEVKEAY YIYSHLGCHE QMWDCEGKEV
60 70 80 90 100
DNFVVKKLLT TYSPFFADNI LGKDIFLTLR VPNPHIEKAE AKILLETLES
110 120 130 140 150
IPRSFDVARI FYKNDIPPIF EVILPMTDTH TAIDNIYQYY ADFVIGKQFK
160 170 180 190 200
RLGGRDTTIA DWIGTFSPKH INVIPLFEDQ TSMLSAHTTV GRYILDKHLP
210 220 230 240 250
YQRVFLARSD PAMNYGLVSA VLLNKIALAN LHRLQEETGV PVYPVIGVGS
260 270 280 290 300
APFRGNLRPD TVDRVSAEYP SAYTFTIQSA FKYDYPPDEA RNAVRALESR
310 320 330 340 350
AVSTPHRVDE TQCLQIMERY TEAYIRELIP LSDIINRIAG HIPGRRKRKL
360 370 380 390 400
HIGLFGYSRN TGGMKLPRAI TFTAALYSIG IPPEILGLSA LSDRDLDFVR
410 420 430 440 450
RIYVNFDRDL CDAARYLNPD SPYLGEGMKD ALLSITGDRI NDDHRQATEN
460 470
ILRALRESRT AEIQSDILHA ANIRKFLG
Length:478
Mass (Da):54,217
Last modified:March 6, 2013 - v1
Checksum:iC286F8F731AEB71F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003167 Genomic DNA. Translation: AGB02060.1.
RefSeqiYP_007248567.1. NC_019943.1.

Genome annotation databases

EnsemblBacteriaiAGB02060; AGB02060; Metfor_1008.
GeneIDi14310321.
KEGGimfo:Metfor_1008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003167 Genomic DNA. Translation: AGB02060.1 .
RefSeqi YP_007248567.1. NC_019943.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGB02060 ; AGB02060 ; Metfor_1008 .
GeneIDi 14310321.
KEGGi mfo:Metfor_1008.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 22288 / NBRC 105244 / SMSPImported.

Entry informationi

Entry nameiL0HDG7_METFS
AccessioniPrimary (citable) accession number: L0HDG7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: October 1, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3