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Protein

Thymidine kinase

Gene

Desdi_3333

Organism
Desulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Desdi_3333Imported
OrganismiDesulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1)Imported
Taxonomic identifieri871963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
ProteomesiUP000010797 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

OMAiSSRVGLC.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0FBY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLYFHFGA MGSSKTANAL LVYHNYIDKG QKALIAKPVI ETRDGDLIKS
60 70 80 90 100
RSGLAGPCIT LEALIEMPFE ALKEYDCIII DEIQFAKEQQ IEFLADIVDT
110 120 130 140 150
LHIPVMCYGL RTDFRGFLFE GSRRMFELAD KIIEIKTVCW CGRKATHNAR
160 170 180
YNEYGIIREG DQIDLGADEK YISLCRKHHQ QGLVRKP
Length:187
Mass (Da):21,349
Last modified:March 5, 2013 - v1
Checksum:iCD2E2A18A41AC5C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003344 Genomic DNA. Translation: AGA70727.1.
RefSeqiYP_007222123.1. NC_019903.1.

Genome annotation databases

EnsemblBacteriaiAGA70727; AGA70727; Desdi_3333.
KEGGiddl:Desdi_3333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003344 Genomic DNA. Translation: AGA70727.1.
RefSeqiYP_007222123.1. NC_019903.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGA70727; AGA70727; Desdi_3333.
KEGGiddl:Desdi_3333.

Phylogenomic databases

OMAiSSRVGLC.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Desulfitobacterium dichloroeliminans LMG P-21439."
    Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Kruse T.
    , de Vos W.M., Boon N., Smidt H., Woyke T.
    Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LMG P-21439 / DCA1Imported.

Entry informationi

Entry nameiL0FBY1_DESDL
AccessioniPrimary (citable) accession number: L0FBY1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 5, 2013
Last sequence update: March 5, 2013
Last modified: March 31, 2015
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.