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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Candidatus Kinetoplastibacterium blastocrithidii (ex Strigomonas culicis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei141 – 1411UniRule annotation
Active sitei582 – 5821UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:CKBE_00241Imported
OrganismiCandidatus Kinetoplastibacterium blastocrithidii (ex Strigomonas culicis)Imported
Taxonomic identifieri1208923 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaKinetoplastibacterium
ProteomesiUP000010470: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

L0B657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQISTLRQEI RLLGKMLGET IYSCEGKRLF DIIESIRRSA IRLRQNSKDP
60 70 80 90 100
DDESLEVYIS KLENNDPNTV ARAFSYFMHL VNIAEDNDQN RRHKAHLSEL
110 120 130 140 150
DYPIRGSLKD VISKLQYNGV TTHEISELLN ESCMSPVLTA HPTEIQRKST
160 170 180 190 200
LDAHRNISRK LIERNNRSNK EDLKEIDLEL LGHIAILWQT RILRYSSLTV
210 220 230 240 250
TDEIENALSY YRSTFLPTIP KLYRDLSNLL NTSENCTSMP LKPFLRMGSW
260 270 280 290 300
IGGDRDGNPN VDELTLEQAM ARQSSVILEH YLKEVFALKT ELSLSNLLVE
310 320 330 340 350
VDEDLLSLAE KSNDMSPHLK DEPYRKALIG IYARLAATSE KLAGKNLARR
360 370 380 390 400
VILPALPYKS SEEFYKDLNT ISSSLEKHHG DLINSLRLKN LQQSVKVFGF
410 420 430 440 450
HLTTLDLRQN SDVHERVLTE LFLQANITLD DKKNRYSDLN EEDKVKILRF
460 470 480 490 500
ELMQGRQLVS PWFEYSAETT KELKIFRAAA KIRKDYGEAA ILQSIVSHTE
510 520 530 540 550
TLSDLLEVLV LQKETGLIKP TYYPHKEHEG LMVVPLFETI TDLQNSSDIM
560 570 580 590 600
SKWMDLPEVN SIIRNSHNNT QEVMLGYSDS NKDGGFLTSN WELYQAERNL
610 620 630 640 650
VNVFRSRNIR LRLFHGRGGS VGRGGGPSFE AILSQPPGAV SGQIRLTEQG
660 670 680 690 700
EIVHGKYNNA EVGKWHLELL VAATLESSLS PRSNKKNVDS TYLDKYGEAM
710 720 730 740 750
SFMSSYAENI YRNLVYEKPG FTEYFFTSTP INEIAELNIG SRPSSRKNLQ
760 770 780 790 800
NIEDLRAIPW SFSWSQCRLM LTSWYGVGSA IEHFIENGTS VISKSKNDRL
810 820 830 840 850
ELLRIMIKEW PAFKTLVSNM EMVLIKSDLS IASCYSKLVP NQTLRNNVFN
860 870 880 890 900
AISLEHRKTI GMLRLLTKRD LLEDNPTLLN ALKERFTYID PLNYLQVELL
910 920 930
RRHRYGHSSI SQSSKEMIKR DIHITINGIA AGLRNSG
Length:937
Mass (Da):107,160
Last modified:March 6, 2013 - v1
Checksum:i6C8E54B7192726A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003733 Genomic DNA. Translation: AFZ83430.1.
RefSeqiYP_007183507.1. NC_019814.1.

Genome annotation databases

EnsemblBacteriaiAFZ83430; AFZ83430; CKBE_00241.
GeneIDi14427092.
KEGGikbl:CKBE_00241.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003733 Genomic DNA. Translation: AFZ83430.1.
RefSeqiYP_007183507.1. NC_019814.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFZ83430; AFZ83430; CKBE_00241.
GeneIDi14427092.
KEGGikbl:CKBE_00241.

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family."
    Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R., Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M., Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M., Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C.
    , Gradia D.F., Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K., Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C., Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P., Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P., de Souza W., Schenkman S., de Vasconcelos A.T.
    PLoS ONE 8:E60209-E60209(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiL0B657_9PROT
AccessioniPrimary (citable) accession number: L0B657
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: March 4, 2015
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.