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K9XMW7

- K9XMW7_STAC7

UniProt

K9XMW7 - K9XMW7_STAC7

Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)
Status
Unreviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (06 Mar 2013)
      Previous versions | rss
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    Functioni

    RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

    Catalytic activityi

    2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
    3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei120 – 1201Substrate; in homodimeric partnerUniRule annotation
    Binding sitei170 – 1701SubstrateUniRule annotation
    Active sitei172 – 1721Proton acceptorUniRule annotation
    Binding sitei174 – 1741SubstrateUniRule annotation
    Metal bindingi198 – 1981Magnesium; via carbamate groupUniRule annotation
    Metal bindingi200 – 2001MagnesiumUniRule annotation
    Metal bindingi201 – 2011MagnesiumUniRule annotation
    Active sitei291 – 2911Proton acceptorUniRule annotation
    Binding sitei292 – 2921SubstrateUniRule annotation
    Binding sitei324 – 3241SubstrateUniRule annotation
    Sitei331 – 3311Transition state stabilizerUniRule annotation
    Binding sitei376 – 3761SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. monooxygenase activity Source: UniProtKB-KW
    3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. photorespiration Source: UniProtKB-KW
    2. reductive pentose-phosphate cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Biological processi

    Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation, PhotorespirationUniRule annotation, PhotosynthesisUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
    Short name:
    RuBisCO large subunitUniRule annotation
    Gene namesi
    Name:cbbLUniRule annotation
    Synonyms:rbcLUniRule annotation
    Ordered Locus Names:Sta7437_0333Imported
    OrganismiStanieria cyanosphaera (strain ATCC 29371 / PCC 7437)Imported
    Taxonomic identifieri111780 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaPleurocapsalesStanieria
    ProteomesiUP000010473: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei198 – 1981N6-carboxylysineUniRule annotation
    Disulfide bondi244 – 244Interchain; in linked formUniRule annotation

    Post-translational modificationi

    The disulfide bond which can form in the large chain dimeric partners within the hexadecamer appears to be associated with oxidative stress and protein turnover.UniRule annotation

    Keywords - PTMi

    Disulfide bondUniRule annotation

    Interactioni

    Subunit structurei

    Heterohexadecamer of 8 large chains and 8 small chains; disulfide-linked. The disulfide link is formed within the large subunit homodimers.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

    Phylogenomic databases

    KOiK01601.
    OMAiFTQDWAS.

    Family and domain databases

    Gene3Di3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPiMF_01338. RuBisCO_L_type1.
    InterProiIPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view]
    PfamiPF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    K9XMW7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVQTKSSSGF KAGVQDYRLT YYTPDYTPKD TDLLACFRMT PQPGVPPEEA    50
    GAAVAAESST GTWTTVWTDG LTDLDRYKGR CYDLEPVPGE DNQYFAFIAY 100
    PLDLFEEGSV TNVLTSLVGN VFGFKALRAL RLEDIRFPVA LIKTFQGPPH 150
    GITVERDKLN KYGRPLLGCT IKPKLGLSAK NYGRAVYECL RGGLDFTKDD 200
    ENINSQPFMR WRDRFLFVQE AIEKSQAETN EIKGHYLNVT AGTCEEMMKR 250
    AEFAKEIGTP IIMHDFLTGG FTANTTLAKY CRDNGLLLHI HRAMHAVIDR 300
    QKNHGIHFRV LAKCLRLSGG DHLHSGTVVG KLEGERGITM GFVDLMREDY 350
    VEEDRSRGIF FTQDYASMPG TMPVASGGIH VWHMPALVEI FGDDSCLQFG 400
    GGTLGHPWGN APGATANRVA LEACVQARNE GRSLAREGND VIREACRWSP 450
    ELAAACELWK EIKFEFEAMD TL 472
    Length:472
    Mass (Da):52,535
    Last modified:March 6, 2013 - v1
    Checksum:i586DDCB635D31207
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003653 Genomic DNA. Translation: AFZ33945.1.
    RefSeqiWP_015191618.1. NC_019748.1.
    YP_007130911.1. NC_019748.1.

    Genome annotation databases

    EnsemblBacteriaiAFZ33945; AFZ33945; Sta7437_0333.
    GeneIDi14161629.
    KEGGiscs:Sta7437_0333.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003653 Genomic DNA. Translation: AFZ33945.1 .
    RefSeqi WP_015191618.1. NC_019748.1.
    YP_007130911.1. NC_019748.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFZ33945 ; AFZ33945 ; Sta7437_0333 .
    GeneIDi 14161629.
    KEGGi scs:Sta7437_0333.

    Phylogenomic databases

    KOi K01601.
    OMAi FTQDWAS.

    Family and domain databases

    Gene3Di 3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPi MF_01338. RuBisCO_L_type1.
    InterProi IPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view ]
    Pfami PF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29371 / PCC 7437Imported.

    Entry informationi

    Entry nameiK9XMW7_STAC7
    AccessioniPrimary (citable) accession number: K9XMW7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2013
    Last sequence update: March 6, 2013
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3