ID   K9PX74_9CHRO            Unreviewed;       564 AA.
AC   K9PX74;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 56.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:AFY38095.1};
GN   ORFNames=Lepto7376_1763 {ECO:0000313|EMBL:AFY38095.1};
OS   [Leptolyngbya] sp. PCC 7376.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Geminocystaceae; Picosynechococcus.
OX   NCBI_TaxID=111781 {ECO:0000313|EMBL:AFY38095.1, ECO:0000313|Proteomes:UP000010389};
RN   [1] {ECO:0000313|EMBL:AFY38095.1, ECO:0000313|Proteomes:UP000010389}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7376 {ECO:0000313|Proteomes:UP000010389};
RG   US DOE Joint Genome Institute;
RA   Gugger M., Coursin T., Rippka R., Tandeau De Marsac N., Huntemann M.,
RA   Wei C.-L., Han J., Detter J.C., Han C., Tapia R., Teshima H., Chen A.,
RA   Krypides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA   Mikhailova N., Pagani I., Pati A., Goodwin L., Peters L., Pitluck S.,
RA   Woyke T., Kerfeld C.;
RT   "Finished genome of Leptolyngbya sp. PCC 7376.";
RL   Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003946; AFY38095.1; -; Genomic_DNA.
DR   AlphaFoldDB; K9PX74; -.
DR   STRING; 111781.Lepto7376_1763; -.
DR   KEGG; lep:Lepto7376_1763; -.
DR   PATRIC; fig|111781.3.peg.2009; -.
DR   eggNOG; COG2206; Bacteria.
DR   eggNOG; COG3437; Bacteria.
DR   HOGENOM; CLU_000445_92_13_3; -.
DR   OrthoDB; 9759601at2; -.
DR   Proteomes; UP000010389; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 2.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR   PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13487; HD_5; 2.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 2.
DR   PROSITE; PS51832; HD_GYP; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AFY38095.1}.
FT   DOMAIN          225..351
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   DOMAIN          354..564
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
SQ   SEQUENCE   564 AA;  64138 MW;  60801C30F7AF9D52 CRC64;
     MTDSSPSLAQ HLEQDHKALM AKIYGGSEAR QRIALIEKLL AIGAALSSAH DLGELLQLIL
     VKCCEITKSD AGSIYLLDSR DTDNPKLIFK AAQNFSLPDI PFKEFSLPLN PKSLAGYVAI
     TGETLSIEDA YKLPDESPYH FDRGFDQKFD YRTCSVLVLP MQDQKANTIG VLQLINRKIE
     SEVKITPENA LHMTQSYSMW EETILRSLAS QGAISIERNL LQDDIENLFE GFVKASVKAI
     ESRDPTTSGH SERVALLTVG LAEEVSRISQ GTLRQEYFGD RQLQEIRYAA LLHDFGKISV
     PEAILNKRQK LYPGDLEVIR QRFAVAKRTL QWECAQQKFQ YLVEHPHAHT EGTSACPHCE
     KIQKMDHEVE ETLDRLDYHL ALIEQFNAPE AIATKKFEIL SEQVFREFTK LAKYRYRDVD
     GKLKPIVNEA DLEQLLLPRG NLNPAERQAI ESHVSQTYEF LKEIPWTKEL KNVPHFAYGH
     HEKLDGTGYP RGLKGDEIPI QTQMMTIADI YDALTAADRP YKKPLPVHVV IRILREEVDR
     NHLNDDLVQA FVNRKVFRVL GHSL
//