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Protein

UDP-glucuronosyltransferase

Gene

Ugt1a6b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-MMU-156588. Glucuronidation.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:Ugt1a6bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:3580629. Ugt1a6b.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei489 – 512HelicalUniRule annotationAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26UniRule annotationAdd BLAST26
ChainiPRO_501075405627 – 531UDP-glucuronosyltransferaseUniRule annotationAdd BLAST505

Expressioni

Gene expression databases

BgeeiENSMUSG00000090145.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108762.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini352 – 395UDPGTInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00760000118949.
KOiK00699.
OMAiESKHYTR.
OrthoDBiEOG091G06JC.
TreeFamiTF315472.

Family and domain databases

InterProiView protein in InterPro
IPR002213. UDP_glucos_trans.
IPR035595. UDP_glycos_trans_CS.
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiView protein in Pfam
PF00201. UDPGT. 1 hit.
PROSITEiView protein in PROSITE
PS00375. UDPGT. 1 hit.

Sequencei

Sequence statusi: Complete.

K9J7B2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACLLPAAQT LPAGFLFLVL WASVLGDKLL VVPQDGSHWL SMKEIVEHLS
60 70 80 90 100
ERGHDIVVLV PEVNLLLGES KYYRRKIFSV PYSLEELQTR FRTFGRNQFV
110 120 130 140 150
PGAPLMGPLR EYRNSMLTLE MFFSNCQSLL KDSATLSFLR ENKFDALFTD
160 170 180 190 200
PAMPCGVILA EYLNLPSVYL FRGFPCSLEH MLGQSPSPVS YVPRFYTKFS
210 220 230 240 250
DHMTFPQRLA NFIVNILENY LYYCLYSKYE IIVTDLLKRD VSLPSLHQNS
260 270 280 290 300
LWLLRYDFVF EYPRPIMPNM IFIGGINCKK KGKLTQEFEA YVNASGEHGI
310 320 330 340 350
VVFSLGSMVS EIPEKKAMEI AEALGRIPQT VLWRYTGTRP SNLAKNTILV
360 370 380 390 400
KWLPQNDLLG HPKTRAFITH SGSHGIYEGI CNGVPMVMMP LFGDQMDNAK
410 420 430 440 450
RMETRGAGVT LNVLEMTADD LENALKTVIN NKSYKENIMR LSSLHKDRPI
460 470 480 490 500
EPLDLAVFWV EYVMRHKGAP HLRPAAHDLT WYQYHSLDVI GFLLAIVLTV
510 520 530
VFIVFKCCAY GCRKCFGGKG RVKKSHKSKT H
Length:531
Mass (Da):60,491
Last modified:February 6, 2013 - v1
Checksum:i9888D0D4C7BBB5A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087780 Genomic DNA. No translation available.
AC087801 Genomic DNA. No translation available.
RefSeqiNP_958812.3. NM_201410.3.
UniGeneiMm.300095.

Genome annotation databases

EnsembliENSMUST00000113137; ENSMUSP00000108762; ENSMUSG00000090145.
ENSMUST00000113138; ENSMUSP00000108763; ENSMUSG00000090145.
GeneIDi394435.
KEGGimmu:394435.
UCSCiuc007byd.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiK9J7B2_MOUSE
AccessioniPrimary (citable) accession number: K9J7B2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: February 6, 2013
Last modified: August 30, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported