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Protein

UDP-glucuronosyltransferase

Gene

Ugt1a6b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:Ugt1a6bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:3580629. Ugt1a6b.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei489 – 51224HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626UniRule annotationAdd
BLAST
Chaini27 – 531505UDP-glucuronosyltransferaseUniRule annotationPRO_5006993037Add
BLAST

Proteomic databases

MaxQBiK9J7B2.

PTM databases

iPTMnetiK9J7B2.
SwissPalmiK9J7B2.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108762.

Structurei

3D structure databases

SMRiK9J7B2. Positions 147-442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00760000118949.
KOiK00699.
OMAiINIGIHE.
OrthoDBiEOG7GBFWS.
PhylomeDBiK9J7B2.
TreeFamiTF315472.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K9J7B2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACLLPAAQT LPAGFLFLVL WASVLGDKLL VVPQDGSHWL SMKEIVEHLS
60 70 80 90 100
ERGHDIVVLV PEVNLLLGES KYYRRKIFSV PYSLEELQTR FRTFGRNQFV
110 120 130 140 150
PGAPLMGPLR EYRNSMLTLE MFFSNCQSLL KDSATLSFLR ENKFDALFTD
160 170 180 190 200
PAMPCGVILA EYLNLPSVYL FRGFPCSLEH MLGQSPSPVS YVPRFYTKFS
210 220 230 240 250
DHMTFPQRLA NFIVNILENY LYYCLYSKYE IIVTDLLKRD VSLPSLHQNS
260 270 280 290 300
LWLLRYDFVF EYPRPIMPNM IFIGGINCKK KGKLTQEFEA YVNASGEHGI
310 320 330 340 350
VVFSLGSMVS EIPEKKAMEI AEALGRIPQT VLWRYTGTRP SNLAKNTILV
360 370 380 390 400
KWLPQNDLLG HPKTRAFITH SGSHGIYEGI CNGVPMVMMP LFGDQMDNAK
410 420 430 440 450
RMETRGAGVT LNVLEMTADD LENALKTVIN NKSYKENIMR LSSLHKDRPI
460 470 480 490 500
EPLDLAVFWV EYVMRHKGAP HLRPAAHDLT WYQYHSLDVI GFLLAIVLTV
510 520 530
VFIVFKCCAY GCRKCFGGKG RVKKSHKSKT H
Length:531
Mass (Da):60,491
Last modified:February 6, 2013 - v1
Checksum:i9888D0D4C7BBB5A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087780 Genomic DNA. No translation available.
AC087801 Genomic DNA. No translation available.
RefSeqiNP_958812.3. NM_201410.3.
UniGeneiMm.300095.

Genome annotation databases

EnsembliENSMUST00000113137; ENSMUSP00000108762; ENSMUSG00000090145.
ENSMUST00000113138; ENSMUSP00000108763; ENSMUSG00000090145.
GeneIDi394435.
KEGGimmu:394435.
UCSCiuc007byd.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087780 Genomic DNA. No translation available.
AC087801 Genomic DNA. No translation available.
RefSeqiNP_958812.3. NM_201410.3.
UniGeneiMm.300095.

3D structure databases

SMRiK9J7B2. Positions 147-442.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108762.

PTM databases

iPTMnetiK9J7B2.
SwissPalmiK9J7B2.

Proteomic databases

MaxQBiK9J7B2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000113137; ENSMUSP00000108762; ENSMUSG00000090145.
ENSMUST00000113138; ENSMUSP00000108763; ENSMUSG00000090145.
GeneIDi394435.
KEGGimmu:394435.
UCSCiuc007byd.2. mouse.

Organism-specific databases

CTDi394435.
MGIiMGI:3580629. Ugt1a6b.

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00760000118949.
KOiK00699.
OMAiINIGIHE.
OrthoDBiEOG7GBFWS.
PhylomeDBiK9J7B2.
TreeFamiTF315472.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (DEC-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiK9J7B2_MOUSE
AccessioniPrimary (citable) accession number: K9J7B2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: February 6, 2013
Last modified: June 8, 2016
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.