ID   K8ESP8_HUMAN            Unreviewed;       273 AA.
AC   K8ESP8;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   03-MAY-2023, entry version 27.
DE   SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CCO56208.1};
DE   Flags: Fragment;
GN   Name=HLA-C {ECO:0000313|EMBL:CCO56208.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CCO56208.1};
RN   [1] {ECO:0000313|EMBL:CCO56208.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wentworth D.E., Dugan V., Halpin R., Lin X., Bera J., Ghedin E.,
RA   Fedorova N., Tsitrin T., Stockwell T., Amedeo P., Bishop B., Edworthy P.,
RA   Gupta N., Katzel D., Li K., Schobel S., Shrivastava S., Thovarai V.,
RA   Wang S., van Doorn R., Mai L.Q., Hang N.L., Phuong H.V., Cuong V.D.,
RA   Thanh L., Thach N.C., Quyen P.D., Bao Y., Sanders R., Dernovoy D.,
RA   Kiryutin B., Lipman D.J., Tatusova T.;
RT   "The NIAID Influenza Genome Sequencing Project.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCO56208.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Masson D.;
RT   "x.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   EMBL; HF548847; CCO56208.1; -; Genomic_DNA.
DR   AlphaFoldDB; K8ESP8; -.
DR   PeptideAtlas; K8ESP8; -.
DR   ChiTaRS; HLA-C; human.
DR   CDD; cd07698; IgC1_MHC_I_alpha3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF252; HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          184..272
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCO56208.1"
FT   NON_TER         273
FT                   /evidence="ECO:0000313|EMBL:CCO56208.1"
SQ   SEQUENCE   273 AA;  31694 MW;  876B7E8595667E5D CRC64;
     SHSMRYFYTA VSRPGRGEPR FIAVGYVDDT QFVRFDSDAA SPRGEPRAPW VEQEGPEYWD
     RETQKYKRQA QTDRVSLRNL RGYYNQSEDG SHTLQWMYGC DLGPDGRLLR GYDQSAYDGK
     DYIALNEDLR SWTAADTAAQ ITQRKWEAAR AAEQWRAYLE GTCVEWLRRY LENGKETLQR
     AEHPKTHVTH HLVSDHEATL RCWALGFYPA EITLTWQRDG EDQTQDTELV ETRPAGDGTF
     QKWAAVVVPS GEEQRYTCHV QHEGLPEPLT LRW
//