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K7X0G5

- K7X0G5_HUMAN

UniProt

K7X0G5 - K7X0G5_HUMAN

Protein
Submitted name:

MHC class I antigen

Gene

HLA-A

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 6 (01 Oct 2014)
      Sequence version 1 (06 Feb 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. peptide antigen binding Source: InterPro

    GO - Biological processi

    1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
    2. immune response Source: InterPro
    3. positive regulation of T cell mediated cytotoxicity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class I antigenImported
    Gene namesi
    Name:HLA-AImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. MHC class I protein complex Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class I family.UniRule annotation
    Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view]
    PRINTSiPR01638. MHCCLASSI.
    SMARTiSM00407. IGc1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    K7X0G5-1 [UniParc]FASTAAdd to Basket

    « Hide

    SHSMRYFTTS VSRPGRGEPR FIAVGYVDDT QFVRFDSDAA SQRMEPRAPW    50
    IEQEGPEYWD LQTRNVKAQS QTDPANLGTL RGYYNQSEAG SHTIQMMYGC 100
    DVGSDGRFLR GYRQDAYDGK DYIALNEDLR SWTAADMAAQ ITQRKWEAAR 150
    VAEQLRAYLE GTCVEWLRRY LENGKETLQR TDAPKTHMTH HAVSDHEATL 200
    RCWALSFYPA EITLTWQRDG EDQTQDTELV ETRPAGDGTF QKWASVVVPS 250
    GQEQRYTCHV QHEGLPKPLT LRW 273
    Length:273
    Mass (Da):31,381
    Last modified:February 6, 2013 - v1
    Checksum:i5D3EBE505C85A275
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei273 – 2731Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX679217 Genomic DNA. Translation: AFX60886.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    JX679217 Genomic DNA. Translation: AFX60886.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.30.500.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011161. MHC_I-like_Ag-recog.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR027648. MHC_I_a.
    IPR001039. MHC_I_a_a1/a2.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00129. MHC_I. 1 hit.
    [Graphical view ]
    PRINTSi PR01638. MHCCLASSI.
    SMARTi SM00407. IGc1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of A*29:47, previously typed as A*29:19, in a Mexican bone marrow donor from the state of Hidalgo, Mexico."
      Alaez C., Munguia A., Flores H.A., Gorodezky C.
      Tissue Antigens 81:454-455(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiK7X0G5_HUMAN
    AccessioniPrimary (citable) accession number: K7X0G5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 6, 2013
    Last sequence update: February 6, 2013
    Last modified: October 1, 2014
    This is version 6 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.