Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

K7WT83 (K7WT83_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

MHC class I antigen EMBL AFW99834.1
Gene names
Name:HLA-A EMBL AFW99834.1
OrganismHomo sapiens (Human) EMBL AFW99834.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the presentation of foreign antigens to the immune system By similarity. SAAS SAAS027648

Sequence similarities

Belongs to the MHC class I family. RuleBase RU004439

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS027648

Sequences

Sequence LengthMass (Da)Tools
K7WT83 [UniParc].

Last modified February 6, 2013. Version 1.
Checksum: CE1BC1CD60CA8FA8

FASTA36540,792
        10         20         30         40         50         60 
MAVMPPRTLL LLLSGALALT QTWAGSHSMR YFFTSVSRPG RGEPRFIAVG YVDDSQFVQF 

        70         80         90        100        110        120 
DSDAASQRME PRAPWIEQEE PEYWDEETRN VKAHSQTNRA NLGTLRGYYN QSEDGSHTIQ 

       130        140        150        160        170        180 
IMYGCDVGSD GRFLRGYRQD AYDGKDYIAL NEDLRSWTAA DMAAQITKRK WEAARRAEQL 

       190        200        210        220        230        240 
RAYLEGECVD GLRRYLENGK ETLQRTDPPK THMTHHPISD HEATLRCWAL SFYPAEITLT 

       250        260        270        280        290        300 
WQRDGEDQTQ DTELVETRPA GDGTFQKWAA VVVPSGKEKR YTCHVQHEGL PEPLTLRWEP 

       310        320        330        340        350        360 
SSQPTIPIVG IIAGLVLLGA VIAGAVVAAV MWRKKSSVRK GGSYSQAASS DSAQGSDVSL 


TACKV 

« Hide

References

[1]"Evolutionary pathway of the A*80:01 allele generation."
Martinez-Laso J., Cervera I.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Genomic full length sequence of HLA-A*80:01 allele."
Balas A., Vicario J.L.
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Confirmatory sequencing of HLA-A*80:01:01:02."
McWhinnie A.J., Robinson J.
Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Peripheral blood EMBL CDO33937.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
JX009131 Genomic DNA. Translation: AFU35545.1.
JX826590 Genomic DNA. Translation: AFW99834.1.
HG965149 Genomic DNA. Translation: CDO33937.1.
UniGeneHs.181244.
Hs.713441.

3D structure databases

ProteinModelPortalK7WT83.
SMRK7WT83. Positions 25-298.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
IPR010579. MHC_I_a_C.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PF06623. MHC_I_C. 1 hit.
[Graphical view]
PRINTSPR01638. MHCCLASSI.
SMARTSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameK7WT83_HUMAN
AccessionPrimary (citable) accession number: K7WT83
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: February 6, 2013
Last modified: July 9, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.