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K7SHJ4

- K7SHJ4_HUMAN

UniProt

K7SHJ4 - K7SHJ4_HUMAN

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Protein
Submitted name:

MHC class I antigen

Gene

HLA-A

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiK7SHJ4.

Structurei

3D structure databases

ProteinModelPortaliK7SHJ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

K7SHJ4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SHSMRYFFTS VSRPGRGEPR FIAVGYVDDT QFVRFDSDAA SQKMEPRAPW
60 70 80 90 100
IEQEGPEYWD QETRNMKAHS QTDRANLGTL RGYYNQSEDG SHTIQIMYGC
110 120 130 140 150
DVGPDGRFLR GYRQDAYDGK DYIALNEDLR SWTAADMAAQ ITKRKWEAVH
160 170 180 190 200
AAEQRRVYLE GRCVDGLRRY LENGKETLQR TDPPKTHMTH HPISDHEATL
210 220 230 240 250
RCWALGFYPA EITLTWQRDG EDQTQDTELV ETRPAGDGTF QKWAAVVVPS
260 270
GEEQRYTCHV QHEGLPKPLT LRW
Length:273
Mass (Da):31,536
Last modified:February 6, 2013 - v1
Checksum:i53578C47C9916BFC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei273 – 2731Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX629459 Genomic DNA. Translation: AFV99140.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX629459 Genomic DNA. Translation: AFV99140.1 .

3D structure databases

ProteinModelPortali K7SHJ4.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi K7SHJ4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-A. human.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SMARTi SM00407. IGc1. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A new allele HLA-A*01."
    Mao W., Huang X., Wang F., Zhang T., Li X., Zhu S., Cheng L., Liao H., Tan X., Huang H., Song Z., Tian Y.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiK7SHJ4_HUMAN
AccessioniPrimary (citable) accession number: K7SHJ4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: February 6, 2013
Last modified: November 26, 2014
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.