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Protein
Submitted name:

Coagulation factor XIII A chain

Gene

F13A1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei318UniRule annotation1
Active sitei377UniRule annotation1
Active sitei400UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-114608. Platelet degranulation.
R-SSC-140875. Common Pathway of Fibrin Clot Formation.

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII A chainImported
Submitted name:
Coagulation factor XIII, A1 polypeptideImported
Gene namesi
Name:F13A1Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSSSCG00000024310.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000030183.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini310 – 403TGcInterPro annotationAdd BLAST94

Phylogenomic databases

eggNOGiENOG410IFMV. Eukaryota.
ENOG410XQEZ. LUCA.
GeneTreeiENSGT00760000119108.
KOiK03917.
OMAiCEEDAVY.
OrthoDBiEOG091G030K.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiView protein in InterPro
IPR034810. Factor_XIII_A.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR036985. Transglutaminase-like_sf.
IPR023608. Transglutaminase_animal.
IPR013808. Transglutaminase_AS.
IPR008958. Transglutaminase_C.
IPR036238. Transglutaminase_C_sf.
IPR001102. Transglutaminase_N.
PANTHERiPTHR11590:SF42. PTHR11590:SF42. 1 hit.
PfamiView protein in Pfam
PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiView protein in SMART
SM00460. TGc. 1 hit.
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiView protein in PROSITE
PS00547. TRANSGLUTAMINASES. 1 hit.

Sequencei

Sequence statusi: Complete.

K7GQL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETPGTGAA FGGRRALPPN TSNAEENDPP TVELQGGLMP RGFNPQDYLN
60 70 80 90 100
VTDVHLFKER WDSNKVDHHT DKYDSKKLIV RRGQPFYIQI DFSRPYDPRR
110 120 130 140 150
DLFRVEYVIG RYPQENKGTY IPVPIVSELQ RGKWGAKVIT TEDRSVRLSV
160 170 180 190 200
QPSPDCIVGK FRMYVAVWTP YGVIRTSRNP ETDTYILFNP WCEEDAVYLD
210 220 230 240 250
NDKEREEYVL NDIGVIFYGE FNDIKSRSWS YGQFEEGILD ACLYMMDRAK
260 270 280 290 300
MDLSGRGNPI KVSRVGSAMV NAKDDEGVLV GSWDNVYSYG VPPSAWTGSV
310 320 330 340 350
DILLEYKSSQ TPVRYGQCWV FAGVFNTFLR CLGIPARVVT NYFSAHDNNA
360 370 380 390 400
NLQLDIFLEE DGNVNSKLTK DSVWNYHCWN EAWMTRPDLP VGFGGWQVVD
410 420 430 440 450
STPQENSDGM YRCGPASVQA IKHGHVCFQF DAPFVFAEVN SDVIYITAKK
460 470 480 490 500
DGTHVVKTLD TTHIGKLIVT KQVGADGMKD ITDTYKFQEG QEEERLALET
510 520 530 540 550
ALMYGAKKPL STEGIPKSRS DIHMDFEVER AVLGRDFKVV LTFRNNSPTR
560 570 580 590 600
YSVTAYLSGN ITFYTGVSKG EFKNETFNVT LEPLSFKTEA VWVRAGEYMG
610 620 630 640 650
QLLEQAFLHF FVTARVNETN DVLAKQKSVV LTIPKISVKV RGTQAVGSDM
660 670 680 690 700
VVTVEFTNPL NEPLQNVWMR LDGPGVTRPL RKIFREIRPN ATVQWEEVCR
710 720 730
PWVSGPRKLM ASMTSDSLRH VYGELNLHIQ RRPSV
Length:735
Mass (Da):83,344
Last modified:January 9, 2013 - v1
Checksum:i2C80EE7A0885EA42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000051 Genomic DNA. No translation available.
GACC01000324 mRNA. Translation: JAA74260.1.
RefSeqiXP_001927665.3. XM_001927630.6.
UniGeneiSsc.26345.

Genome annotation databases

EnsembliENSSSCT00000035671; ENSSSCP00000030183; ENSSSCG00000024310.
GeneIDi100153504.
KEGGissc:100153504.

Similar proteinsi

Entry informationi

Entry nameiK7GQL2_PIG
AccessioniPrimary (citable) accession number: K7GQL2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 25, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported