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K7GQL2

- K7GQL2_PIG

UniProt

K7GQL2 - K7GQL2_PIG

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Protein
Submitted name: Coagulation factor XIII, A1 polypeptide
Gene
F13A1
Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei318 – 3181 By similarity
Active sitei377 – 3771 By similarityUniRule annotation
Active sitei400 – 4001 By similarity
Metal bindingi440 – 4401Calcium By similarityUniRule annotation
Metal bindingi442 – 4421Calcium By similarityUniRule annotation
Metal bindingi489 – 4891Calcium By similarityUniRule annotation
Metal bindingi494 – 4941Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor XIII, A1 polypeptideImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:F13A1Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
ProteomesiUP000008227: Chromosome 7

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK03917.
OrthoDBiEOG7WT40M.
TreeFamiTF324278.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

K7GQL2-1 [UniParc]FASTAAdd to Basket

« Hide

MAETPGTGAA FGGRRALPPN TSNAEENDPP TVELQGGLMP RGFNPQDYLN    50
VTDVHLFKER WDSNKVDHHT DKYDSKKLIV RRGQPFYIQI DFSRPYDPRR 100
DLFRVEYVIG RYPQENKGTY IPVPIVSELQ RGKWGAKVIT TEDRSVRLSV 150
QPSPDCIVGK FRMYVAVWTP YGVIRTSRNP ETDTYILFNP WCEEDAVYLD 200
NDKEREEYVL NDIGVIFYGE FNDIKSRSWS YGQFEEGILD ACLYMMDRAK 250
MDLSGRGNPI KVSRVGSAMV NAKDDEGVLV GSWDNVYSYG VPPSAWTGSV 300
DILLEYKSSQ TPVRYGQCWV FAGVFNTFLR CLGIPARVVT NYFSAHDNNA 350
NLQLDIFLEE DGNVNSKLTK DSVWNYHCWN EAWMTRPDLP VGFGGWQVVD 400
STPQENSDGM YRCGPASVQA IKHGHVCFQF DAPFVFAEVN SDVIYITAKK 450
DGTHVVKTLD TTHIGKLIVT KQVGADGMKD ITDTYKFQEG QEEERLALET 500
ALMYGAKKPL STEGIPKSRS DIHMDFEVER AVLGRDFKVV LTFRNNSPTR 550
YSVTAYLSGN ITFYTGVSKG EFKNETFNVT LEPLSFKTEA VWVRAGEYMG 600
QLLEQAFLHF FVTARVNETN DVLAKQKSVV LTIPKISVKV RGTQAVGSDM 650
VVTVEFTNPL NEPLQNVWMR LDGPGVTRPL RKIFREIRPN ATVQWEEVCR 700
PWVSGPRKLM ASMTSDSLRH VYGELNLHIQ RRPSV 735
Length:735
Mass (Da):83,344
Last modified:January 9, 2013 - v1
Checksum:i2C80EE7A0885EA42
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT956082 Genomic DNA. No translation available.
CU469172 Genomic DNA. No translation available.
GACC01000324 mRNA. Translation: JAA74260.1.
RefSeqiXP_001927665.3. XM_001927630.5.

Genome annotation databases

EnsembliENSSSCT00000035671; ENSSSCP00000030183; ENSSSCG00000024310.
GeneIDi100153504.
KEGGissc:100153504.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT956082 Genomic DNA. No translation available.
CU469172 Genomic DNA. No translation available.
GACC01000324 mRNA. Translation: JAA74260.1 .
RefSeqi XP_001927665.3. XM_001927630.5.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSSSCT00000035671 ; ENSSSCP00000030183 ; ENSSSCG00000024310 .
GeneIDi 100153504.
KEGGi ssc:100153504.

Organism-specific databases

CTDi 2162.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K03917.
OrthoDBi EOG7WT40M.
TreeFami TF324278.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Porcine genome sequencing project
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (NOV-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  3. "Global Gene Expression Profiling of Alveolar Macrophages by Deep Sequencing."
    Dawson H.D., Chen C.T.
    Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiK7GQL2_PIG
AccessioniPrimary (citable) accession number: K7GQL2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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