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Protein
Submitted name:

Erbb2 interacting protein

Gene

ERBIN

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-1227986 Signaling by ERBB2
R-SSC-8863795 Downregulation of ERBB2 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Erbb2 interacting proteinImported
Gene namesi
Name:ERBINImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiK7GKZ4
PRIDEiK7GKZ4

Expressioni

Gene expression databases

BgeeiENSSSCG00000016954
ExpressionAtlasiK7GKZ4 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000028522

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1357 – 1446PDZInterPro annotationAdd BLAST90

Phylogenomic databases

eggNOGiKOG1286 Eukaryota
COG0531 LUCA
GeneTreeiENSGT00840000129686
InParanoidiK7GKZ4
OrthoDBiEOG091G01EF

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR032927 Erbin
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
PANTHERiPTHR44896 PTHR44896, 1 hit
PfamiView protein in Pfam
PF13855 LRR_8, 4 hits
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 11 hits
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 13 hits
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Complete.

K7GKZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKKKKNLSK DGSHMRNVGS IKKHQGDKFN LVCLKMTTKR SLFVRLVPCR
60 70 80 90 100
CLRGEEETVT TLDYSHCSLE QVPKEIFTFE KTLEELYLDA NQIEELPKQL
110 120 130 140 150
FNCQSLHKLS LPDNDLTTLP ASIANLINLR ELDVSKNGIQ EFPENIKNCK
160 170 180 190 200
VLTVVEASVN PISKLPDGFS QLLNLTQLYL NDAFLEFLPA NFGRLTKLQI
210 220 230 240 250
LELRENQLKM LPKTMNRLTQ LERLDLGSNE FTEVPEVLEQ LSGLKEFWMD
260 270 280 290 300
GNRLTFIPGF IGSLKQLTYL DVSKNNIEVV EEGISACENL QDLLLSSNSL
310 320 330 340 350
QQLPETIGSL KNVTTLKIDE NQLIYLPDSI GGLISIEELD CSFNELEALP
360 370 380 390 400
SSVGQLTNIR TFAADHNYLQ QLPPEIGSWK NITVLFLHSN KLETLPEEMG
410 420 430 440 450
DMQKLKVINL SDNRLKNLPF SFTKLQQLTA MWLSDNQSKP LIPLQKETDS
460 470 480 490 500
ETQKMVLTNY MFPQQPRTED VMFISDNESF NPSLWEEQRK QRAQVAFECD
510 520 530 540 550
EDKDEREAPP REGNLKRYPT PYPDELKNMV KTVQTIVHRL KDEETNEDSG
560 570 580 590 600
KDLKPHEDQQ VVNNEVGVKT SESATPVKSK ADEREKYMIG NSIQKTSEPE
610 620 630 640 650
AEVSPGSLPV TANMKASENL KHIVNHDDVF EESEELSSDE EMKMAEMRPP
660 670 680 690 700
LIETSINQPK VVALSNNKKD DTKDTDSLSD EVTHNSNQNN SNCSSPSRMS
710 720 730 740 750
DSVSLNTDSS QDTSLCSPVK QTHIGINSKI RQEDENFNSL LQNGDILNHS
760 770 780 790 800
TEEKFKVPDK KDFNLPEYDL NIEERLVLIE KGIDSTATCD ESHKLDHINM
810 820 830 840 850
NLNKLVTNDT FQPEIVERSK TQDIVLGAGF LSRNAEGEAE HLENGNEYPN
860 870 880 890 900
LECINKVNGH SEETPQSPRR TESHDTDSSI DVGLSKSTED LSPQRSGPVG
910 920 930 940 950
PVVKSHSITN METGGLKIYD IHSDNGPQQP SATVKVTSTI DGKNIVRSKS
960 970 980 990 1000
ATLLYDQPLQ VFTGSSSSSD LISGTKAIFK FDSNHNPEEL NIIRGPTTSG
1010 1020 1030 1040 1050
PQSTPQIYGP PQYNIQYSSG TAVKDTLWHS KQNPQIDHVS FPPQRLPRSE
1060 1070 1080 1090 1100
STENHSHAKH SANMNFSNHN NVRASTGYHL HQRLGPGRHG EMWAVSPNDR
1110 1120 1130 1140 1150
LIPGATRTTI QRQSSVSSAA SVNLGEPGPM RRAQVPEGDY LSYRELHSVG
1160 1170 1180 1190 1200
RTPPMMSGSQ RPLSARTYSI DGQNASRPQS ARPSVSEIPE RTMSVSDFNY
1210 1220 1230 1240 1250
SRTSPSKRPN ARVGSEHSLL DPPGKSKVPH DWREQVLRHI EAKKLEKHPQ
1260 1270 1280 1290 1300
TSCPGDPCQD DIFISGQQNY SSATLSHKDV LPDSLMKMPL SNGQMGQPLR
1310 1320 1330 1340 1350
PQANYSQIHH PIPQASVARH PSREQLIDYL MLKVAHQPPY TQPHCSPRQG
1360 1370 1380 1390 1400
HELARQEIRV RVEKDPELGF SISGGVGGRG NPFRPDDDGI FVTRVQPEGP
1410 1420 1430 1440
ASKLLQPGDK IIQANGYSFI NIEHGQAVSL LKTFQNTVEL IVLREVSS
Length:1,448
Mass (Da):162,186
Last modified:November 22, 2017 - v2
Checksum:i4CA569B87659B446
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000102 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSSSCT00000035098; ENSSSCP00000028522; ENSSSCG00000016954

Similar proteinsi

Entry informationi

Entry nameiK7GKZ4_PIG
AccessioniPrimary (citable) accession number: K7GKZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: November 22, 2017
Last modified: May 23, 2018
This is version 37 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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