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Protein
Submitted name:

Sphingosine-1-phosphate receptor 1

Gene

S1PR1

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Sphingosine-1-phosphate receptor 1Imported
Gene namesi
Name:S1PR1Imported
OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
Taxonomic identifieri13735 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
Proteomesi
  • UP000007267 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei48 – 69HelicalSequence analysisAdd BLAST22
Transmembranei81 – 102HelicalSequence analysisAdd BLAST22
Transmembranei122 – 138HelicalSequence analysisAdd BLAST17
Transmembranei159 – 180HelicalSequence analysisAdd BLAST22
Transmembranei200 – 222HelicalSequence analysisAdd BLAST23
Transmembranei251 – 273HelicalSequence analysisAdd BLAST23
Transmembranei293 – 312HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000001760.

Structurei

3D structure databases

ProteinModelPortaliK7F150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 309G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIA7. Eukaryota.
ENOG410XQD3. LUCA.
GeneTreeiENSGT00760000118804.
OMAiCFIACWA.
OrthoDBiEOG091G0DD4.
TreeFamiTF330052.

Family and domain databases

InterProiView protein in InterPro
IPR000987. EDG1_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004061. S1P_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00642. EDG1RECEPTOR.
PR00237. GPCRRHODOPSN.
PR01523. S1PRECEPTOR.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

K7F150-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTSSRQKK ILNDTVSDYV NSEIIKKHYN YTGKLNEKAD SGIKVTSVVF
60 70 80 90 100
IIICCFIILE NIFVLLTIWK TKKFHRPMYY FIGNLALSDL LAGVAYTANL
110 120 130 140 150
LLSGHKTYSL TPAQWFVREG SMFVALSASV FSLLAIAIER YITMLKMKLH
160 170 180 190 200
NGSNSFRSFL LISACWVISM ILGGLPIMGW NCLDQLHSCS TVLPLYHKHY
210 220 230 240 250
ILFCTTVFTG LLLSIVVLYC RIYSMVRTRS RRLTFRKNFS KATKSSEKSL
260 270 280 290 300
ALLKTVIIVL SAFIACWSPL FILLLLDVGC KVKACSILFK AEYFLVLAVL
310 320 330 340 350
NSATNPIIYT LTNKEMRRAF IKILCCCKCP SADSGAKFKR PIIGGMEFSR
360 370 380
SKSDNSSHPQ KDEGDCPETI MSSGNVTSSS
Length:380
Mass (Da):42,545
Last modified:January 9, 2013 - v1
Checksum:i2C540CA6FC1BD8A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01063383 Genomic DNA. No translation available.
RefSeqiXP_006119863.1. XM_006119801.2.
XP_006119864.1. XM_006119802.2.
XP_006119866.1. XM_006119804.2.
XP_006119867.1. XM_006119805.2.

Genome annotation databases

EnsembliENSPSIT00000001767; ENSPSIP00000001760; ENSPSIG00000001767.
GeneIDi102461395.

Similar proteinsi

Entry informationi

Entry nameiK7F150_PELSI
AccessioniPrimary (citable) accession number: K7F150
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 27, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported