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Protein
Submitted name:

Mothers against decapentaplegic homolog 2

Gene

SMAD2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mothers against decapentaplegic homolog 2Imported
Gene namesi
Name:SMAD2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:6768. SMAD2.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175387.

PTM / Processingi

Proteomic databases

MaxQBiK7ERC7.
PaxDbiK7ERC7.
PeptideAtlasiK7ERC7.
PRIDEiK7ERC7.

Expressioni

Gene expression databases

BgeeiENSG00000175387.
ExpressionAtlasiK7ERC7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliK7ERC7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 137MH1 (MAD homology 1)InterPro annotationAdd BLAST128

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.

Family and domain databases

Gene3Di3.90.520.10. 1 hit.
InterProiView protein in InterPro
IPR013790. Dwarfin.
IPR003619. MAD_homology1_Dwarfin-type.
IPR013019. MAD_homology_MH1.
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiView protein in Pfam
PF03165. MH1. 1 hit.
SMARTiView protein in SMART
SM00523. DWA. 1 hit.
SUPFAMiSSF56366. SSF56366. 2 hits.
PROSITEiView protein in PROSITE
PS51075. MH1. 1 hit.

Sequencei

Sequence statusi: Fragment.

K7ERC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK
60 70 80 90 100
KLKKTGRLDE LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG
110 120 130
LYSFSEQTRS LDGRLQVSHR KGLPHVIYCR LWRWPDL
Length:137
Mass (Da):15,248
Last modified:January 9, 2013 - v1
Checksum:i370D592457B5497A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei137Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026898 Genomic DNA. No translation available.
AC120349 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000587421; ENSP00000468202; ENSG00000175387.
UCSCiuc060oyc.1. human.

Similar proteinsi

Entry informationi

Entry nameiK7ERC7_HUMAN
AccessioniPrimary (citable) accession number: K7ERC7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: August 30, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported