Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

cAMP-dependent protein kinase catalytic subunit alpha

Gene

PRKACA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. cAMP-dependent protein kinase activity Source: Ensembl

GO - Biological processi

  1. cellular response to parathyroid hormone stimulus Source: Ensembl
  2. mesoderm formation Source: Ensembl
  3. negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning Source: Ensembl
  4. neural tube closure Source: Ensembl
  5. peptidyl-serine phosphorylation Source: Ensembl
  6. peptidyl-threonine phosphorylation Source: Ensembl
  7. positive regulation of cell cycle arrest Source: Ensembl
  8. positive regulation of protein export from nucleus Source: Ensembl
  9. protein autophosphorylation Source: Ensembl
  10. regulation of protein processing Source: Ensembl
  11. regulation of synaptic transmission Source: Ensembl
  12. sperm capacitation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-dependent protein kinase catalytic subunit alphaImported
Gene namesi
Name:PRKACAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:9380. PRKACA.

Subcellular locationi

GO - Cellular componenti

  1. ciliary base Source: Ensembl
  2. mitochondrion Source: Ensembl
  3. neuromuscular junction Source: Ensembl
  4. nucleus Source: Ensembl
  5. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiK7EMV1. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00780000121885.

Sequencei

Sequence statusi: Fragment.

K7EMV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MLVKHKETGN HYAMKILDKQ KVVKL
Length:25
Mass (Da):2,953
Last modified:January 9, 2013 - v1
Checksum:i494DECFA080070D1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei25 – 251Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022098 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000589284; ENSP00000466660; ENSG00000072062.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022098 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000589284; ENSP00000466660; ENSG00000072062.

Organism-specific databases

HGNCiHGNC:9380. PRKACA.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00780000121885.

Miscellaneous databases

ChiTaRSiPRKACA. human.

Gene expression databases

ExpressionAtlasiK7EMV1. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (OCT-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiK7EMV1_HUMAN
AccessioniPrimary (citable) accession number: K7EMV1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: March 4, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationMaxQB annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.