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Protein
Submitted name:

Glucosidase 2 subunit beta

Gene

PRKCSH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi222 – 233PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Glucosidase 2 subunit betaImported
Gene namesi
Name:PRKCSHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000130175.9
HGNCiHGNC:9411 PRKCSH

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130175

PTM / Processingi

Proteomic databases

EPDiK7ELL7
MaxQBiK7ELL7
PeptideAtlasiK7ELL7
PRIDEiK7ELL7

Expressioni

Gene expression databases

BgeeiENSG00000130175
ExpressionAtlasiK7ELL7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ELL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 244EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili145 – 172Sequence analysisAdd BLAST28
Coiled coili188 – 208Sequence analysisAdd BLAST21
Coiled coili309 – 338Sequence analysisAdd BLAST30
Coiled coili374 – 404Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2397 Eukaryota
ENOG410XPE3 LUCA
GeneTreeiENSGT00510000047770
OMAiCYELTTN
OrthoDBiEOG091G06YU

Family and domain databases

CDDicd00112 LDLa, 1 hit
Gene3Di2.70.130.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR026874 Glucosidase_2_bsu
IPR036055 LDL_receptor-like_sf
IPR002172 LDrepeatLR_classA_rpt
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR036607 PRKCSH
IPR028146 PRKCSH_N
PANTHERiPTHR12630:SF1 PTHR12630:SF1, 1 hit
PfamiView protein in Pfam
PF13202 EF-hand_5, 1 hit
PF12999 PRKCSH-like, 1 hit
PF13015 PRKCSH_1, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF57424 SSF57424, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

K7ELL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLPLLLLLP MCWAVEVKRP RGVSLTNHHF YDESKPFTCL DGSATIPFDQ
60 70 80 90 100
VNDDYCDCKD GSDEPGTAAC PNGSFHCTNT GYKPLYIPSN RVNDGVCDCC
110 120 130 140 150
DGTDEYNSGV ICENTCKEKG RKERESLQQM AEVTREGFRL KKILIEDWKK
160 170 180 190 200
AREEKQKKLI ELQAGKKSLE DQVEMLRTVK EEAEKPEREA KEQHQKLWEE
210 220 230 240 250
QLAAAKAQQE QELAADAFKE LDDDMDGTVS VTELQTHPEL DTDGDGALSE
260 270 280 290 300
AEAQALLSGD TQTDATSFYD RVWAAIRDKY RSEALPTDLP APSAPDLTEP
310 320 330 340 350
KEEQPPVPSS PTEEEEEEEE EEEEEAEEEE EEEDSEVQGE QPKEAPPPLS
360 370 380 390 400
PPQPASPAEE DKMPPYDEQT QAFIDAAQEA RNKFEEAERS LKDMEESIRN
410 420 430 440 450
LEQEISFDFG PNGEFAYLYS QCYELTTNEY VYRLCPFKLV SQKPKLGGSP
460 470 480 490 500
TSLGTWGSWI GPDHDKFSAM KYEQGTGCWQ GPNRSTTVRL LCGKETMVTS
510 520 530
TTEPSRCEYL MELMTPAACP EPPPEAPTED DHDEL
Length:535
Mass (Da):60,192
Last modified:January 9, 2013 - v1
Checksum:i8A6ECA276C7B3C26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008481 Genomic DNA No translation available.
RefSeqiNP_001276032.1, NM_001289103.1
NP_001276033.1, NM_001289104.1
XP_011526432.1, XM_011528130.1
UniGeneiHs.610830

Genome annotation databases

EnsembliENST00000592741; ENSP00000466134; ENSG00000130175
GeneIDi5589
UCSCiuc002mrv.3 human

Similar proteinsi

Entry informationi

Entry nameiK7ELL7_HUMAN
AccessioniPrimary (citable) accession number: K7ELL7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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