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Protein
Submitted name:

Mothers against decapentaplegic homolog 4

Gene

SMAD4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mothers against decapentaplegic homolog 4Imported
Gene namesi
Name:SMAD4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:6770. SMAD4.

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141646.

PTM / Processingi

Proteomic databases

MaxQBiK7ELK2.
PaxDbiK7ELK2.
PeptideAtlasiK7ELK2.

Expressioni

Gene expression databases

BgeeiENSG00000141646.
ExpressionAtlasiK7ELK2. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 82MH2 (MAD homology 2)InterPro annotationAdd BLAST82

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.

Family and domain databases

Gene3Di2.60.200.10. 1 hit.
InterProiView protein in InterPro
IPR013790. Dwarfin.
IPR017855. SMAD_dom-like.
IPR001132. SMAD_dom_Dwarfin-type.
IPR008984. SMAD_FHA_domain.
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiView protein in Pfam
PF03166. MH2. 1 hit.
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiView protein in PROSITE
PS51076. MH2. 1 hit.

Sequencei

Sequence statusi: Fragment.

K7ELK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
YYLDREAGRA PGDAVHKIYP SAYIKVFDLR QCHRQMQQQA ATAQAAAAAQ
60 70 80
AAAVAGNIPG PGSVGGIAPA ISKYAFHSFL KV
Length:82
Mass (Da):8,630
Last modified:January 9, 2013 - v1
Checksum:iC85045A7077FC0C7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091551 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000593223; ENSP00000466118; ENSG00000141646.
UCSCiuc060pfn.1. human.

Entry informationi

Entry nameiK7ELK2_HUMAN
AccessioniPrimary (citable) accession number: K7ELK2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: July 5, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported