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K7EK80

- K7EK80_HUMAN

UniProt

K7EK80 - K7EK80_HUMAN

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Protein
Submitted name:

Zinc finger protein 540

Gene

ZNF540

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 540Imported
Gene namesi
Name:ZNF540Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:25331. ZNF540.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: HPA
  2. intracellular membrane-bounded organelle Source: HPA
  3. nucleus Source: HPA
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiK7EK80. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliK7EK80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118783.

Family and domain databases

Gene3Di3.30.160.60. 13 hits.
InterProiIPR001909. Krueppel-associated_box.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

K7EK80-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAHALVTFRD VAIDFSQKEW ECLDTTQRKL YRDVMLENYN NLVSLGYSGS
60 70 80 90 100
KPDVITLLEQ GKEPCVVARD VTGRQCPGLL SRHKTKKLSS EKDIHEISLS
110 120 130 140 150
KESIIEKSKT LRLKGSIFRN EWQNKSEFEG QQGLKERSIS QKKIVSKKMS
160 170 180 190 200
TDRKRPSFTL NQRIHNSEKS CDSHLVQHGK IDSDVKHDCK ECGSTFNNVY
210 220 230 240 250
QLTLHQKIHT GEKSCKCEKC GKVFSHSYQL TLHQRFHTGE KPYECQECGK
260 270 280 290 300
TFTLYPQLNR HQKIHTGKKP YMCKKCDKGF FSRLELTQHK RIHTGKKSYE
310 320 330 340 350
CKECGKVFQL IFYFKEHERI HTGKKPYECK ECGKAFSVCG QLTRHQKIHT
360 370 380 390 400
GVKPYECKEC GKTFRLSFYL TEHRRTHAGK KPYECKECGK SFNVRGQLNR
410 420 430 440 450
HKTIHTGIKP FACKVCEKAF SYSGDLRVHS RIHTGEKPYE CKECGKAFML
460 470 480 490 500
RSVLTEHQRL HTGVKPYECK ECGKTFRVRS QISLHKKIHT DVKPYKCVRC
510 520 530 540 550
GKTFRFGFYL TEHQRIHTGE KPYKCKECGK AFIRRGNLKE HLKIHSGLKP

YD
Length:552
Mass (Da):64,296
Last modified:January 9, 2013 - v1
Checksum:i8A2B183E4886C189
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei552 – 5521Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC022148 Genomic DNA. No translation available.
KF573660 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000586134; ENSP00000465503; ENSG00000171817.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC022148 Genomic DNA. No translation available.
KF573660 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali K7EK80.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000586134 ; ENSP00000465503 ; ENSG00000171817 .

Organism-specific databases

HGNCi HGNC:25331. ZNF540.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118783.

Gene expression databases

ExpressionAtlasi K7EK80. baseline and differential.

Family and domain databases

Gene3Di 3.30.160.60. 13 hits.
InterProi IPR001909. Krueppel-associated_box.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF01352. KRAB. 1 hit.
[Graphical view ]
SMARTi SM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view ]
SUPFAMi SSF109640. SSF109640. 1 hit.
PROSITEi PS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 13 hits.
PS50157. ZINC_FINGER_C2H2_2. 13 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (NOV-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiK7EK80_HUMAN
AccessioniPrimary (citable) accession number: K7EK80
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 29, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3