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K7EK80

- K7EK80_HUMAN

UniProt

K7EK80 - K7EK80_HUMAN

Protein
Submitted name:

Zinc finger protein 540

Gene

ZNF540

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (09 Jan 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. nucleic acid binding Source: InterPro

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Zinc finger protein 540Imported
    Gene namesi
    Name:ZNF540Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:25331. ZNF540.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. intracellular membrane-bounded organelle Source: HPA
    3. nucleus Source: HPA

    Expressioni

    Gene expression databases

    ArrayExpressiK7EK80.

    Structurei

    3D structure databases

    ProteinModelPortaliK7EK80.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    RepeatSAAS annotation, Zinc-fingerSAAS annotation

    Family and domain databases

    Gene3Di3.30.160.60. 13 hits.
    InterProiIPR001909. Krueppel-associated_box.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF01352. KRAB. 1 hit.
    [Graphical view]
    SMARTiSM00349. KRAB. 1 hit.
    SM00355. ZnF_C2H2. 13 hits.
    [Graphical view]
    SUPFAMiSSF109640. SSF109640. 1 hit.
    PROSITEiPS50805. KRAB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 13 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    K7EK80-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHALVTFRD VAIDFSQKEW ECLDTTQRKL YRDVMLENYN NLVSLGYSGS    50
    KPDVITLLEQ GKEPCVVARD VTGRQCPGLL SRHKTKKLSS EKDIHEISLS 100
    KESIIEKSKT LRLKGSIFRN EWQNKSEFEG QQGLKERSIS QKKIVSKKMS 150
    TDRKRPSFTL NQRIHNSEKS CDSHLVQHGK IDSDVKHDCK ECGSTFNNVY 200
    QLTLHQKIHT GEKSCKCEKC GKVFSHSYQL TLHQRFHTGE KPYECQECGK 250
    TFTLYPQLNR HQKIHTGKKP YMCKKCDKGF FSRLELTQHK RIHTGKKSYE 300
    CKECGKVFQL IFYFKEHERI HTGKKPYECK ECGKAFSVCG QLTRHQKIHT 350
    GVKPYECKEC GKTFRLSFYL TEHRRTHAGK KPYECKECGK SFNVRGQLNR 400
    HKTIHTGIKP FACKVCEKAF SYSGDLRVHS RIHTGEKPYE CKECGKAFML 450
    RSVLTEHQRL HTGVKPYECK ECGKTFRVRS QISLHKKIHT DVKPYKCVRC 500
    GKTFRFGFYL TEHQRIHTGE KPYKCKECGK AFIRRGNLKE HLKIHSGLKP 550
    YD 552
    Length:552
    Mass (Da):64,296
    Last modified:January 9, 2013 - v1
    Checksum:i8A2B183E4886C189
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei552 – 5521Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC022148 Genomic DNA. No translation available.
    KF573660 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000586134; ENSP00000465503; ENSG00000171817.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC022148 Genomic DNA. No translation available.
    KF573660 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali K7EK80.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000586134 ; ENSP00000465503 ; ENSG00000171817 .

    Organism-specific databases

    HGNCi HGNC:25331. ZNF540.
    GenAtlasi Search...

    Gene expression databases

    ArrayExpressi K7EK80.

    Family and domain databases

    Gene3Di 3.30.160.60. 13 hits.
    InterProi IPR001909. Krueppel-associated_box.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF01352. KRAB. 1 hit.
    [Graphical view ]
    SMARTi SM00349. KRAB. 1 hit.
    SM00355. ZnF_C2H2. 13 hits.
    [Graphical view ]
    SUPFAMi SSF109640. SSF109640. 1 hit.
    PROSITEi PS50805. KRAB. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 13 hits.
    PS50157. ZINC_FINGER_C2H2_2. 13 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (NOV-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiK7EK80_HUMAN
    AccessioniPrimary (citable) accession number: K7EK80
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2013
    Last sequence update: January 9, 2013
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3