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Protein
Submitted name:

Polypyrimidine tract-binding protein 1

Gene

PTBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Polypyrimidine tract-binding protein 1Imported
Gene namesi
Name:PTBP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000011304.17
HGNCiHGNC:9583 PTBP1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000011304

PTM / Processingi

Proteomic databases

MaxQBiK7EK45
PeptideAtlasiK7EK45
PRIDEiK7EK45

Expressioni

Gene expression databases

BgeeiENSG00000011304
ExpressionAtlasiK7EK45 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EK45
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 85RRMInterPro annotationAdd BLAST77

Phylogenomic databases

GeneTreeiENSGT00550000074508

Family and domain databases

CDDicd12693 RRM2_PTBP1_like, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034798 PTBP1/2/3_RRM2
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Fragment.

K7EK45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XMAGQSPVLR IIVENLFYPV TLDVLHQIFS KFGTVLKIIT FTKNNQFQAL
60 70 80 90 100
LQYADPVSAQ HAKLSLDGQN IYNACCTLRI DFSKLTSLNV KYNNDKSRDY
110 120 130 140 150
TRPDLPSGDS QPSLDQTMAA AFGAPGIISA SPYAGAGFPP TFAIPQAAGL
160 170 180 190 200
SVPNVHGALA PLAIPSAAAA AAAAGRIAIP GLAGAGNSVL LVSNLNPERV
210 220 230 240 250
KILFNKKENA LVQMADGNQA QLAMSHLNGH KLHGKPIRIT LSKHQNVQLP

REGQED
Length:256
Mass (Da):27,225
Last modified:January 9, 2013 - v1
Checksum:i4A270526DC92DF82
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei256Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006273 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000585956; ENSP00000465451; ENSG00000011304
UCSCiuc060qrf.1 human

Similar proteinsi

Entry informationi

Entry nameiK7EK45_HUMAN
AccessioniPrimary (citable) accession number: K7EK45
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health