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Protein
Submitted name:

Nuclear factor 1 X-type

Gene

NFIX

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi17 – 183CTF/NF-IPROSITE-ProRule annotationAdd BLAST167

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorPROSITE-ProRule annotation, DNA-bindingPROSITE-ProRule annotation
Biological processDNA replicationPROSITE-ProRule annotation, Transcription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor 1 X-typeImported
Gene namesi
Name:NFIXImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000008441.16.
HGNCiHGNC:7788. NFIX.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000008441.

PTM / Processingi

Proteomic databases

MaxQBiK7EJB0.
PaxDbiK7EJB0.
PeptideAtlasiK7EJB0.
PRIDEiK7EJB0.

Expressioni

Gene expression databases

BgeeiENSG00000008441.
ExpressionAtlasiK7EJB0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliK7EJB0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 183CTF/NF-IInterPro annotationAdd BLAST167

Sequence similaritiesi

Belongs to the CTF/NF-I family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3663. Eukaryota.
ENOG410Y16G. LUCA.
GeneTreeiENSGT00390000009905.

Family and domain databases

InterProiView protein in InterPro
IPR000647. CTF/NFI.
IPR020604. CTF/NFI_DNA-bd-dom.
IPR019739. CTF/NFI_DNA-bd_CS.
IPR019548. CTF/NFI_DNA-bd_N.
IPR003619. MAD_homology1_Dwarfin-type.
PANTHERiPTHR11492. PTHR11492. 1 hit.
PfamiView protein in Pfam
PF03165. MH1. 1 hit.
PF10524. NfI_DNAbd_pre-N. 1 hit.
SMARTiView protein in SMART
SM00523. DWA. 1 hit.
PROSITEiView protein in PROSITE
PS00349. CTF_NFI_1. 1 hit.
PS51080. CTF_NFI_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

K7EJB0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGATEPGGDT SSVCVWTATL SVRVCDEFHP FIEALLPHVR AFSYTWFNLQ
60 70 80 90 100
ARKRKYFKKH EKRMSKDEER AVKDELLGEK PEIKQKWASR LLAKLRKDIR
110 120 130 140 150
PEFREDFVLT ITGKKPPCCV LSNPDQKGKI RRIDCLRQAD KVWRLDLVMV
160 170 180
ILFKGIPLES TDGERLYKSP QCSNPGLCVQ PHH
Length:183
Mass (Da):21,195
Last modified:January 9, 2013 - v1
Checksum:iC09AB77949C996B2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei183Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007787 Genomic DNA. No translation available.
AC022152 Genomic DNA. No translation available.
AC138474 Genomic DNA. No translation available.
KF456509 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000591028; ENSP00000465094; ENSG00000008441.
UCSCiuc060ugq.1. human.

Similar proteinsi

Entry informationi

Entry nameiK7EJB0_HUMAN
AccessioniPrimary (citable) accession number: K7EJB0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 27, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported