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Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei284 – 309HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiK7DVA1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini187 – 275Ig-likeInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di1.20.5.100. 1 hit.
2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiView protein in InterPro
IPR021157. Cyt_c1_TM_anchor_C.
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR037055. MHC_I-like_Ag-recog_sf.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
PRINTSiPR01638. MHCCLASSI.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Fragment.

K7DVA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
WACSHSMRYF YTAVSRPGRG EPRFIAVGYV DDTQFVQFDS DAASPRGEPR
60 70 80 90 100
APWVEQEGPE YWDRETQKYK RQAQTDRVSL RNLRGYYNQS EAGSHTLQRM
110 120 130 140 150
YGCDLGPDGR LLRGYNQFAY DGKDYIALNE DLRSWTAADT AAQITQRKWE
160 170 180 190 200
AARTAEQLRA YLEGTCVEWL RRYPENGKKT LQRAEHPKTH VTHHPVSDHE
210 220 230 240 250
ATLRCWALGF YPAEITLTWQ RDGEDQTQDT ELVETRPAGD GTFQKWAAVV
260 270 280 290 300
VPSGEEQRYT CHVQHEGLPE PLTLRWGPSS QPTIPIVGIV AGLAVLAVLA
310 320
VLGAVMAVVM CRRKSSGGKG GSYSQAASS
Length:329
Mass (Da):36,988
Last modified:January 9, 2013 - v1
Checksum:i59E5133EA1005252
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei329Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN887337 mRNA. Translation: AFH75432.1.
UniGeneiHs.656020.
Hs.743218.

Similar proteinsi

Entry informationi

Entry nameiK7DVA1_HUMAN
AccessioniPrimary (citable) accession number: K7DVA1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 25, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.